摘要
目的探究肝硬化合并糖尿病临床特征、预后以及糖代谢指标。方法选取该院201 1年3月—2014年5月期间收治的48例肝硬化合并糖尿病患者,并将其分为肝硬化合并糖尿病(27例)组以及肝硬化无糖尿病患者(21例)。比较两组患者的预后以及糖代谢指标。结果肝硬化合并糖尿病组中酒精性肝硬化发生率为12.5%,肝硬化无糖尿病组中酒精肝发生率为6.25%;肝硬化合并糖尿病组的住院时间、Child—Pugh评分、电解质紊乱产生率以及病死率等相关指标均低于肝硬化无糖尿病组;其肝硬化合并糖尿病组空腹血糖以及糖化血红蛋白水平明显小于肝硬化无糖尿病组,通过对比,差异有统计学意义(P<0.05);两组间HOMA—IR通过对比,差异不具有统计学意义(P>0.05)。结论肝硬化合并糖尿病患者和肝硬化无糖尿病患者进行对比,肝硬化合并糖尿病患者具有较差的肝功能,同时死亡率高于硬化无糖尿病患者。
Objective To explore the clinical features and prognosis of hepatocirrhosis with diabetes and glucose metabolism.Selection.Methods Our hospital in March 2011-May 2014＇ admitted during the period of 48 cases of cirrhosis combined with diabetes,and incorporating it into liver cirrhosis diabetes group（27 cases） and liver cirrhosis patients without diabetes（21 cases）.Compare two groups of the prognosis of patients with indicators and glucose metabolism.Results The incidence of hepatocirrhosis with alcoholic liver cirrhosis in diabetes group was 12.5%,the group without diabetes incidence of alcohol liver cirrhosis is 6.25%;Hepatocirrhosis with diabetes group of Child- Pugh score,length of hospital stay,electrolyte disorder related parameters of production rate and case fatality rate is lower than cirrhosis without diabetes group;The hepatocirrhosis with diabetes group of fasting glucose,and glycosylated hemoglobin levels are much smaller than liver cirrhosis group without diabetes,by contrast,significant difference,statistically significant（P〈0.05）;HOMA- IR by comparing between the two groups,there was no significant difference,not statistically significant（P〈0.05）.Conclusion Liver cirrhosis combined with diabetes and liver cirrhosis patients without diabetes,liver cirrhosis combined with diabetes has a poor liver function,and sclerosis of mortality is higher than patients without diabetes.
出处
《糖尿病新世界》
2015年第11期144-145,共2页
Diabetes New World Magazine
关键词
肝硬化合并糖尿病
糖代谢指标
预后
研究观察
Hepatocirrhosis with diabetes
Sugar metabolism index
The prognosis
Study
