摘要
目的探讨术前纤维蛋白原水平与乳腺癌患者预后之间的关系。方法回顾分析168例接受根治性手术的乳腺癌患者临床资料,探讨术前纤维蛋白原与乳腺癌患者临床病理因素及预后的关系。结果术前纤维蛋白原与临床分期和淋巴结转移显著相关;晚期患者的术前纤维蛋白原水平显著高于早期患者,有淋巴结转移患者的术前纤维蛋白原水平显著高于无淋巴转移者(P<0.05);术前纤维蛋白原水平、临床分期和淋巴结转移是影响乳腺癌患者预后的独立风险因素(P<0.05)。结论术前纤维蛋白原水平与乳腺癌临床分期及淋巴结转移有关,是影响乳腺癌预后的独立危险因素。
Objective To investigate the prognostic value of preoperative serum fibrinogen in patients with breast cancer patients after curative resection. Methods A total of 168 cases of patients with breast cancer were enrolled in this study. The medical records of patients were reviewed and the relationship between preoperative serum fibrinogen levels and clinical pathological features and prognosis were analyzed. Results The preoperative level of fibrinogen was significantly associated with TNM stage and lymph node metastasis. Preoperative fibrinogen was significantly higher in the group with advanced TNM stage and lymph node metastasis. Fibrinogen, lymph node metastasis were recognized as independent risk factors affecting the prognosis（P〈0.05）. Conclusion In the present study, preoperative level of fibrinogen correlated to TNM staging and lymph node metastasis. A high preoperative fibrinogen level could predict poor prognosis for patientswith breastcancerafter curative resection.
出处
《岭南现代临床外科》
2015年第4期417-419,共3页
Lingnan Modern Clinics in Surgery
关键词
乳腺癌
纤维蛋白原
预后
Breast cancer
Fibrinogen
Prognosis
