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microRNA-433与肿瘤 被引量：2

microRNA-433 and cancer
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摘要 microRNA是一种由17-25个核苷酸组成的小的非编码单链RNA。miR-433是miRNA的一种,它在肿瘤中的表达是变化的。miR-433能够影响肿瘤细胞的增殖、侵袭和迁移能力,且与肿瘤化疗药的药物敏感性相关。miR-433的表达与肿瘤的类型和分期相关。本文将对近年来关于miR-433与肿瘤的研究进展进行综述。 microRNAs are small non-coding single-stranded RNAs with sizes of 17-25 nucleotides, miR-433 is one kind of miRNAs and the expression of miR-433 is changeable in cancers, affects the proliferation, invasion and migration of cancer cells and is related to the sensibility of chemotherapeutic drugs. The expression of miR-433 is also related to the type and grade of cancer.
作者 王香琛 吕晓红 马垚 张雅芳
机构地区 哈尔滨医科大学人体解剖学教研室
出处 《解剖科学进展》 CAS 2015年第4期423-425,429,共4页 Progress of Anatomical Sciences
基金 高等学校博士学科点专项科研基金(No.20102307110016)
关键词 microRNA-433 核苷酸组成 药物敏感性 正常胃组织 荧光素酶 细胞转染 分子标记物 正常胃粘膜 结构域 临床病理因子
分类号 R730.2 [医药卫生—肿瘤]
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参考文献19

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二级参考文献42

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解剖科学进展
2015年 第4期

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