摘要
目的研制用于捕集空气中环氧乙烷（EO）的固体吸附剂管,并建立配套的气相色谱法。方法基于EO能与氢溴酸发生开环反应生成2-溴乙醇的原理,采用研制的固体吸附剂管捕集空气中EO,在捕集过程中反应生成2-溴乙醇,经二甲基甲酰胺解吸、毛细管色谱柱分离后,运用电子俘获检测器对其进行检测。结果在0.12~97.29 mg/L范围内,EO质量浓度与实验测得峰面积呈线性关系,相关系数为0.999 97;批内精密度相对标准偏差（RSD）为1.27%~1.96%,批间精密度RSD为2.49%~3.83%;平均解吸效率为93.55%~98.49%;平均衍生效率为95.67%~97.38%;定量下限为0.03 mg/L;最低定量质量浓度为0.01 mg/m3（以采集3.0 L空气计）。样品在室温下可保存6 d,在4℃冰箱中至少可保存8 d,这比国家标准方法需要当天尽快测定这一要求有了明显改进。结论研制的固体吸附剂管及其配套的测定方法适合于空气中EO的采样以及检测。
Objective New solid sorbent tubes were developed for capturing ethylene oxide（EO） in the air and the matched dissolved desorption-gas chromatography was established. Methods Based on the principle that EO could react with hydrobromic acid,the new solid sorbent tubes were developed,which were dipped with 5%（V/V） hydrobromic acid-methanol solution. The reaction product, generated in the process of capture,was desorbed with dimethylformamide, separated through capillary chromatographic column separation,and then detected by GC-ECD. Results The linear range of EO was 0.12- 97.29 mg/L,and the related coefficients was 0.99997. The minimum quantification concentration was 0.01 mg/m3（sample volume was 3.0L）.The average derivative efficiency was 95.67%- 97.38%. The average desorption efficiency was 93.55%- 98.49%. The intraday relative standard deviation（RSD） was 1.27%- 1.96%,and the interday RSD was 2.49%- 3.83%. The samples could be stored at room temperature for at least 6 days,and 8 days at 4 centigrade. Conclusion The new solid sorbent tubes containing hydrobromic acid were developed and could be applicable for collection of ethylene oxide（EO）in the air.
出处
《职业卫生与应急救援》
2015年第3期193-197,共5页
Occupational Health and Emergency Rescue
基金
广东省医学科研基金(编号:A2014072
B2013028)
广州市职业环境与健康效应实验室建设项目(编号:2014SY000020)
广州市"121人才梯队工程"后备人才项目
广东省"十二五"医学重点专科(编号:粤卫函[2012]20号)
广州市医学重点学科建设项目(编号:穗卫科[2013]21号)
