摘要
目的探讨活血祛瘀方对慢性肾脏病(CKD)3期血瘀证患者的临床疗效。方法按就诊顺序随机分为两组,最终纳入统计的治疗组27例,对照组27例,对照组针对危险因素等治疗,治疗组在对照组治疗的基础上加用活血祛瘀方治疗,检测治疗前后血肌酐(SCr)、血尿素氮(BUN)、肾小球滤过率(GFR)、24h尿蛋白定量。结果活血祛瘀方治疗组能明显改善CKD3期血瘀证患者的临床症状,降低SCr、24h尿蛋白定量,使GFR有显著的增加,两组治疗后比较统计学有显著性差异。结论活血祛瘀方能减少蛋白尿,改善肾功能,尤其能明显升高GFR,具有稳定GFR作用。
Objective To investigate the curative effects of HUO- XUE- QU- YU recipe for Blood Stasis of chronic kidney disease（ CKD） Stage 3.Methods The patients were randomly divided into conventional western medicine treated group（ control group,27cases） and conventional western medicine plus Huo-Xue-Qu-Yu recipe treated group（ treatment group,27cases）.We examined the serum- creatinine（ SCr）,blood urea nitrogen（ BUN）,glomerular filtration rate（ GFR） and proteinuria（ pro） in27 cases of CKD Stage 3 patients treated by Huo-Xue-Qu-Yu recipe,compared with conventional medicine treated group with western medicine.Results Combination of Chinese and western medicine can improve symptoms and decrease SCr,proteinuria,and increase the level of GFR in the patients with Blood Stasis of CKD Stage 3.Conclusion Huo-Xue-Qu-Yu recipe plus conventional western medicine can reduce proteinuria and improve renal function,can effectively increased significantly the GFR in the patients with CKD Stage 3.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2015年第7期1664-1666,共3页
Lishizhen Medicine and Materia Medica Research
基金
国家自然科学基金(No.81173219)
科技部中医药行业科研专项(No.201007005)
高等学校博士学科点专项科研基金资助项目(No.20093107110006)
上海市科委创新行动计划项目(No.11DZ1973100)
上海市高校创新团队建设项目
关键词
活血祛瘀方
血瘀证
慢性肾脏病3期
Huo-Xue-Qu-Yu recipe
Blood Stasis
Chronic Kidney Disease Stage 3
