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国际泌尿病理协会前列腺癌Gleason分级系统穿刺活检标本病理形态分析及Gleason评分 被引量:2

Pathologic diagnosis and Gleason grading of the ISUP prostatic carcinoma Gleason grading system by needle biopsy specimens
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摘要 目的:观察前列腺癌穿刺活检标本病理形态学改变并进行Gleason评分。方法:收集31例前列腺穿刺活检确诊为前列腺癌的标本,采用2005国际泌尿病理协会(ISUP)修订标准进行评分(GS)。结果:Gleason 6分占16.1%(5/31),7分占61.3%(19/31),8~10分占22.6%(7/31)。以3级为主要结构占48.4%(15/31),次要结构占51.6%(16/31);以4级为主要结构占41.9%(13/31),次要结构占35.5%(11/31);以5级为主要结构成分9.7%(3/31),次要结构成分占12.9%(4/31)。GS=6分占16.1%(5/31),GS≥7分占83.9%(25/31)。结论:2005国际泌尿病理协会前列腺癌Gleason分级系统,对于穿刺活检标本Gleason评分较高,其中3级和4级为常见结构,3级结构更为常见。修订后的Gleason分级系统判断标准明确,容易掌握,有助于对前列腺癌穿刺标本进行规范分级。 Objective:To observe pathological changes in prostatic carcinoma needle biopsy samples and give Gleason Scores. Methods:31 needle biopsy specimens of diagnosed prostatic cancer patients were collected from Jan. 2010 to Oct. 2014. Gleason scoring and the studies were conducted according to the 2005 refinements of the ISUP. Results: The resuits showed that GS 6,7,8 - 10 were each seen in 16.1% (5/31) ,61.3% ( 19/31 ) ,and 22.6% (7/31) of the cases, respectively . Of which, GS 6 accounted for 16.1% (5.31) and GS≥7 accounted for 83.9% (25/31). Conclusions: The study showed higher Gleason scores following the 2005 updated ISUP prostate carcinoma Gleason grading system. Pattern 3 and 4 were common patterns, while pattern 3 occurring more often. 2005 ISUP Prostate carcinoma Gleason grading system provided more precise and practical criteria for assigning Gleason scores to needle biopsy specimens, allowing for improved clinical prognosis and treatment.
出处 《赣南医学院学报》 2015年第3期361-364,共4页 JOURNAL OF GANNAN MEDICAL UNIVERSITY
基金 东莞市科技局2014年度科技项目(编号:2014105101094)
关键词 前列腺癌 穿刺活检 GLEASON分级 国际泌尿病理协会 Prostate carcinoma Needle biopsy Gleason grading International Society of Urological Pathology (ISUP)
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  • 1汪朔,谢立平,沈华锋,郑祥毅,秦杰,白宇,张晨光,陈昭典,蔡松良,张志根,任国平,王丽君,余心如.346例前列腺癌的Gleason评分分布特征及其与临床分期的关系[J].中华男科学杂志,2006,12(8):689-692. 被引量:12
  • 2曾瑄,武莎斐,许群,肖雨,刘彤华.前列腺癌8号染色体改变与Gleason评分之间的相关性[J].中华病理学杂志,2006,35(9):523-528. 被引量:5
  • 3谢立平,蒋建平,沈华锋,郑祥毅,秦杰,张晨光,白宇,陈昭典,蔡松良,张志根,任国平,王丽君,余心如.前列腺癌血清PSA、f/tPSA与Gleason评分、临床分期的相关性研究[J].中国男科学杂志,2007,21(3):14-17. 被引量:12
  • 4许克新,王晓峰,佟雪松.血清PSA与Gleason分级及临床分期的相关性研究[J].中国男科学杂志,2007,21(5):31-34. 被引量:7
  • 5Eskew LA, Bare RL, McCullough DL. Systematic 5 region prostate biopsy is superior to sextant method diagnosing carcinoma of the prostate. J Urol 1997; 157(1): 199-202.
  • 6Egevad L, Granfors T, Karlberg L, et al. Prognostic value of the Gleason score in prostate cancer. BJU Int 2002; 89(6): 538-542.
  • 7Noguchi M, Stamey TA, McNeal JE, et al. Relationship between systematic biopsies and histological features of 222 radical prostatectomy specimens: lack of prediction of tumor significance for men with nonpalpable prostate cancer. J Urol 2001; 166(1): 104-109.
  • 8Steinberg DM, Sauvageot J, Piantadosi S. Correlation of prostate needle biopsy and radical prostatectomy Gleason grade in academic and community settings. Am J Surg Pathol 1997; 21(5): 566-576.
  • 9Epstein JI, Potter SR. The pathological interpretation and significance of prostate needle biopsy findings implications and current controversies. J Urol 2001; 166(2): 402-410.
  • 10Bulbul MA, EI-Hout Y, Haddad M, et al. Pathological correlation between needle biopsy and radical prostatectomy specimen in patients with localized prostate cancer. Can Urol Assoc J 2007; 1(3):264-266.

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