摘要
目的探讨云南大理白族自治州成人糖尿病前期及糖尿病的流行现状并分析相关危险因素。方法采用多阶段、随机、整群抽样方法,对大理白族自治州主城区18岁以上常驻居民进行年度健康体检,共抽取5 439例为调查对象,以问卷收集资料并进行体格检查及实验室检查,采用横断面调查,统计不同年龄、性别组人群的糖尿病前期及糖尿病患病率并对相关危险因素进行分析。结果①云南大理白族自治州成人年龄标化后糖尿病前期患病率为20.55%(男性23.39%,女性18.74%),标化后糖尿病患病率为11.32%(男性12.21%,女性11.14%),男性糖尿病前期以及糖尿病患病率高于女性(P<0.01);②随着年龄的增长,各年龄组糖尿病前期患病率逐渐增长,男性为5.18%、10.44%、26.32%、32.19%、39.30%,女性为5.87%、8.13%、21.82%、26.89%,28.77%;糖尿病的发病率随着年龄的增长亦逐渐增长,男性为1.55%、3.84%、13.43%、20.52%、22.97%,女性为1.51%、3.73%、11.48%、16.41%、19.14%。③空腹血糖受损(IFG)、单纯糖耐量受损(IGT)、联合空腹血糖受损和糖耐量受损(IFG+IGT)、新诊断糖尿病、已经诊断糖尿病患病率分别为1.56%、9.64%、10.28%、6.74%、5.21%;在糖尿病前期患者中,IFG、IGT、IFG+IGT构成比分别占7.25%、44.89%、47.86%;在糖尿病患者中,新诊断的糖尿病占56.40%,已经诊断糖尿病占43.60%。④Logistic回归分析显示:年龄、性别、收缩压、体质量指数、静息心率、甘油三酯、总胆固醇、血尿酸、糖尿病家族史、脑卒中家族史为2型糖尿病的危险因素,高密度脂蛋白胆固醇、教育程度为保护性因素。结论云南大理白族自治州成人糖尿病前期以及糖尿病流行状况严峻,该地区应建立健康的生活方式,强调血压、血糖、血脂、体质量的综合控制,加强糖尿病教育是防治2型糖尿病发生的重要措施。
Objective In order to investigate epidemic status of prediabetes and diabetes in adult population of Dali Bai Autonomous Prefecture of Yunnan, and analyze related risk factors. Methods A multi-stage and cluster sampling method, population-based cross-sectional study on diabetes was performed in 5 439 randomly selected adults, aged above 18 years, living in the main city of Dali Bai Autonomous Prefecture. A questionnaire was used to collect information and physical examinations and laboratory tests were conducted, the prevalence of prediabetes and diabetes population in different age and gender, and related risk factors were analyzed. Results ① The age-standardized prevalence of prediatetes and diabetes were 20.55%（23. 39% for men and 18.74% for women） and 11. 32% （12.21% for men and 11.14% for women）, respectively. The prevalence of prediabetes and diabetes in males were significantly higher than in females（ P 〈0.01）. ② The prevalence of prediabetes increased with age（5.18%, 10.44% ,26.32%, 32.19% ,39.30% for male, 5.87%, 8.13%, 21.82%, 26.89%,28.77% for female）. The prevalence of diabetes increased with age（1.55%,3.84%,13.43%,20.52%,22.97% for male, 1.51%,3.73%,11.48%,16.41%, 19.14% for female）, respectively. ③ The prevalence of impaired fasting glucose （IFG）, simple impaired glucose tolerance （IGT）, joint impaired fasting glucose and impaired glucose tolerance （IFG ＋ IGT）, the new diagnosis of diabetes, the diabetes diagnosed were 1. 560%, 9.64% and 10.28%, 6.74%, 5.21%, respectively; in patients with prediabetes, proportion of IFG, IGT, IFG ＋ IGT respectively accounting for 7.25% ,44.89% ,47.86% ; in diabetic patients, the new diagnosis of diabetes accounting for 56.40%, the diabetes diagnosed accounting for 43.60%. ④Logistic regression analysis showed that age, gender, systolic blood pressure, body mass index, resting heart rate, triglycerides, total cholesterol, uric acid, family history of diabetes, family history of stroke were the risk factors for type 2 diabetes, high density lipoprotein cholesterol and education were protective factors. Conclusion The epidemic situation of prediabetes and diabetes is grim in adult population of Dali Bai Autonomous Prefecture of Yunnan, the region should establish healthy lifestyle, and control the blood pressure, blood sugar, blood lipids, body mass of adults. Diabetes education is an important measure for prevention and treatment of type 2 diabetes mellitus.
出处
《临床荟萃》
CAS
2015年第8期909-914,共6页
Clinical Focus
关键词
糖尿病
流行病学方法
危险因素
diabetes mellitus
epidemiologic methods
risk factors
