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胆囊、胆总管结石疾病的微创个性化临床治疗研究 被引量:3

Individualized and minimally invasive treatment for gallstone and choledocholithiasis
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摘要 目的探讨胆囊、胆总管结石疾病微创个体化临床治疗效果。方法收集我院行微创个体化治疗的320例胆囊、胆总管结石患者为观察组,选取同期单纯腹腔镜治疗胆囊、胆总管结石的患者120例为对照组,比较两组患者手术时间、术中出血量、胃肠功能恢复时间、住院时间、结石清除率及肝功能、并发症。结果观察组手术时间、术中出血量、胃肠功能恢复时间及住院时间均少于对照组[(37.4±5.2)minVS.(42.7±6.1)min,(44.3±6.3)ml VS.(45.8±7.1)ml,(19.2±4.6)h vs.(24.1±5.1)h.(3.2±0.7)d VS.(4.4±1.0)d,P〈0.05]。观察组结石清除率与对照组比较,差异无统计学意义(99.06%VS.98.33%,P〉0,05)。观察组AST和ALB水平均低于对照组[(35.3±8.5)U/L vs.(46.3±9.1)U/L,(41.4±4.2)g/L。VS.(43.4±4.8)g/L,P〈0.05]。观察组并发症发生率低于对照组(1.88%vs.8.33%.P〈0.05)。结论根据患者病情个体化微创治疗胆囊、胆总管结石,可减小对患者的创伤,提高治疗效果,降低并发症发生率。 Objective To investigate the therapeutic effect of individualized and minimally invasive treatment for gallstone and choledocholithiasis. Methods 320 patients with gallstone and/or choledocholithiasis treated with individualized and minimally invasive treatment were selected as an observation group and 120 treated with only laparoscopic cholecystectomy a control group. The operation time, intraoperative bleeding volume, gastrointestinal function recovery time, hospital stay, calculi clearance rate, liver function, and incidence of complications were compared between these two groups. Results The operation time, intraoperative bleeding volume, gastrointestinal function recovery time, and hospital stay were less in the observation group than in the control group [(37.4±5.2) rain vs. (42.7±6.1) min, (44.3±6.3) ml vs. (45.8±7.1) ml, (19.24±4.6) h vs. (24.1±5.1) h, and (3.2±0.7) d vs. (4.4±1.0) d, P 〈0.05]. There was no statistical difference in calculi clearance rate between the observation group and the control group (99.06% vs. 98.33%, P〉 0.05). The AST and ALB levels were lower in the observation group than in the control group [(35.3±8.5) U/L vs. (46.3±9.1) U/L and (41.4 ± 4.2) g/L vs. (43.4±4.8) g/L, P 〈0.05]. The incidence of complications was lower in the observation group than in the control group (1.88% vs. 8.33%, P 〈0.05), Conclusions Individualized and minimally invasive treatment for gallstone and choledocholithiasis according to the patients' disease conditions can reduce the patients' surgical trauma, improve treatment effect, and reduce the incidence of complications.
出处 《国际医药卫生导报》 2015年第15期2121-2124,共4页 International Medicine and Health Guidance News
关键词 胆囊结石 胆总管结石 微创个体化 治疗效果 Gallstone Choledocholithiasis Individualized and minimally invasive Treatment effect
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