摘要
目的:探讨关节腔注射玻璃酸钠治疗老年骨性膝关节炎的临床疗效。方法:选取2013年10月至2014年10月收治的骨性膝关节炎患者60例,随机分为观察组和对照组,每组30例,观察组患者给予关节腔注射玻璃酸钠,每周1次、连续5周;对照组患者采取口服甾体类药物与外用涂抹止痛药(如扶他林等)进行治疗。比较两组患者治疗前后的临床情况及膝关节功能的恢复情况。结果:观察组和对照组患者治疗前后的临床症状相比差异有统计学意义(P<0.05);观察组患者的骨关节评分低于对照组(P<0.05);治疗后随访1个月,膝关节功能恢复的总有效率,观察组为93.3%、对照组为76.7%,两组比较差异有统计学意义(P<0.05);日常活动能力恢复情况比较观察组患者优于对照组(P<0.05)。结论:关节腔注射玻璃酸钠在治疗老年骨性关节炎中有较好的临床疗效,可以有效缓解患者关节疼痛,对膝关节恢复有较好功效。
Objective： To investigate the clinical efficacy of intra-articular injection of sodium hyaluronate in the treatment of elderly knee osteoarthritis. Methods： 60 patients with knee osteoarthritis admitted by our hospital from October 2013 to October 2014 were randomly divided into two groups（ the observation group and the control group）,30 cases in each group. The observation group was treated with intra-articular injection of sodium hyaluronate,once a week for five weeks. The control group was treated with oral steroids and topical analgesics smear（ as Voltaren,etc.）. The clinical situation and recovery of knee joint function before and after treatment between the two groups were compared. Results： Clinical symptoms were significantly different before and after treatment between the two groups（ P〈0. 05）. Bone and joint score in the observation group was significantly lower than that in the control group（ P〈0. 05）. One month of follow-up after treatment showed that the total effective rate of knee joint function recovery was 93. 3 % in the observation group and 76. 7% in the control group,with statistically significant difference between the two groups（ P〈0. 05）. The recovery of the ability of daily activities in the observation group was better than that in the control group,and the difference was statistically significant（ P〈0. 05）. Conclusion： The intra-articular injection of sodium hyaluronate is of better clinical efficacy in the treatment of osteoarthritis in the elderly,which can effectively relieve joint pain,having a better effect on the recovery of knee joint.
出处
《包头医学院学报》
CAS
2015年第7期28-29,共2页
Journal of Baotou Medical College
关键词
关节腔注射
玻璃酸钠
骨性膝关节炎
老年
Intra-articular injection
Sodium hyaluronate
Knee osteoarthritis
Elderly
