摘要
目的探析沙丁胺醇联合布地奈德雾化吸入治疗支气管哮喘急性发作的临床效果。方法选择2013年6月-2014年6月本院收治的支气管哮喘急性发作患者180例作为研究对象并进行分组治疗,对照组90例给予地塞米松磷酸钠注射液进行治疗,观察组90例给予沙丁胺醇联合布地奈德雾化吸入治疗。观察比较两组患者治疗前后肺功能改善指标及疗效。结果两组患者治疗前肺功能指标比较,差异无统计学意义（P〉0.05）;治疗2周后,观察组相关指标均明显优于对照组,差异有统计学意义（P〈0.05）;观察组治疗过程中的胸闷气短、肺部哮鸣音及咳嗽等临床症状存在时间明显短于对照组,差异有统计学意义（P〈0.05）;观察组总有效率为96.67%,显著高于对照组的86.67%;观察组患者均未发生不良反应,对照组不良反应发生率为6.67%,差异有统计学意义（P〈0.05）。结论沙丁胺醇联合布地奈德雾化吸入治疗支气管哮喘急性发作患者,效果显著,可尽快改善患者的肺功能,不良反应发生率低,安全性高,值得推广应用。
Objective To study effect of atomization inhalation of albuterol combined with budesonide in the treatment of acute bronchial asthma. Methods From June 2013 to June 2014,180 cases of acute attack of bronchial asthma patients in our hospital were randomly divided into two groups, with 90 cases in each group.The control groups were given dexamethasone sodium phosphate injection treatment,and observation group were given atomization inhalation albuterol combined with budesonide.Lung function index and curative effect between two groups before and after treatment were compared. Results Two groups＇s patients before treatment the lung function indexes had no significant difference （P〉0.05）,2 weeks after treatment,the indicators in observation group was significantly better than that of control group,with statistical difference （P〈0.05）;The course of treatment,observation group＇s patients chest condition, lung cough,wheezing sound duration of symptoms was significantly less than control group respectively,with statistical difference （P〈O.OS）;Total effective rate of observation group was 96.67%,significantly higher than 86.67% of control group,and the incidence of adverse reactions of observation group was 0.00%,significantly lower than 6.67% of control group,with statistical difference （P〈0.05）. Conclusion Albuterol combined with budesonide treating acute onset of bronchial asthma patients,can have a significant effect,and improve lung function in patients as soon as possible,and has low incidence of adverse reactions,high safety,and it is of popularization and application.
出处
《中国当代医药》
2015年第21期89-91,共3页
China Modern Medicine
关键词
沙丁胺醇
布地奈德
支气管哮喘
Bronchial asthma
Acute attack
Albuterol
Budesonide
Atomization inhalation
