摘要
脓毒症是由细菌、病毒或真菌感染诱发的全身炎症反应,可以导致休克、多器官功能障碍综合征甚至死亡。目前脓毒症已成为重症监护病房(ICU)患者死亡的主要原因。急性肾损伤(AKI)是脓毒症发展过程中最常见、最严重的并发症之一,以急性肾衰竭(ARF)为特征,其发病率随脓毒症的严重程度加重而升高,并明显高于其他因素。随着对脓毒症研究的不断深入,人们对脓毒症引起的肾损伤的治疗也有了新的认识,其中改善肾脏灌注颇受关注。本文就调节肾脏灌注的措施作一综述。
Sepsis is the result of systemic inflammatory reaction induced by bacteria, virus or fungus infection, and it can lead to shock, multiple organ dysfunction syndrome, and even death. It has become the main cause for death of the patients in intensive care unit （ICU）. Acute kidney injury （AKI） is one of the most common, and the most serious complications in the course of sepsis, and it is characterized by acute renal failure （ARF）. The incidence of AKI would climb with the severity of sepsis, and it is significantly more eminent than the other factors. Along with the advancement in the research on sepsis, a new understanding in the treatment of renal injury caused by sepsis is gradually obtained, and attention is given to the improvement of renal perfusion. In this review, we review the measures for adjusting the renal perfusion.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2015年第8期677-680,共4页
Medical Journal of Chinese People's Liberation Army
关键词
脓毒症
急性肾损伤
再灌注损伤
sepsis
acute kidney iniury
reperfusion injury
