摘要
目的:了解2010-2013年某院报告为严重的药品不良反应的发生情况,促进临床安全合理用药。方法:回顾性调查某院121例严重的不良反应病例报告,从患者的一般情况、药品种类、不良反应类型等方面进行统计和分析。结果:121例严重的不良反应中,男性略多于女性,以≥60岁老年患者居多;怀疑药品以抗感染药物最多,代表药物为头孢哌酮钠舒巴坦钠;涉及药品中注射剂型最多,口服给药方式最常见;累及系统或器官以消化系统居首,其次为全身损害;临床表现以过敏为多。结论:应继续加强临床药品不良反应尤其是严重的药品不良反应的监测,为临床安全合理用药提供依据。
OBJECTIVE To improve level of rational drug use by realizing the regularity of serious adverse drug reactions（ADR）from2010 to 2013 in this hospital.METHODS A total of 121 cases of serious ADR were collected from this hospital,and general conditions,drug types and serious ADR were analyzed statistically.RESULTS Of 121 ADR reports,most were reported in male patients,patients in the age group of≥60 years.The drugs that induced more ADR cases were antimicrobial antimicrobialananana antimicrobial injection.Mostly involved system of ADR was gastrointestinal system.CONCLUSIONMore attention should be paid to monitoring of serious ADR by drug use units to avoid or reduce incidence of ADR and improve level of rational drug use.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2015年第14期1314-1317,共4页
Chinese Journal of Hospital Pharmacy
关键词
严重的药品不良反应
回顾性分析
合理用药
serious adverse drug reaction
retrospective analysis
rational drug use
