摘要
目的探讨贝母瓜蒌散联合奥美拉唑治疗反流性咽喉炎的临床疗效。方法选取反流性咽喉炎患者120例,随机分为治疗组与对照组,每组60例。对照组给予奥美拉唑肠溶片(质子泵抑制剂)和枸橼酸莫沙必利(促胃动力药)治疗,治疗组在对照组基础上应用中药贝母瓜蒌散(海螵蛸、瓜蒌、贝母等)进行治疗。比较2组治疗效果,反流症状指数与反流体征指数。结果治疗组治疗后总效率为88.3%,明显高于对照组的58.3%,差异有统计学意义(P<0.05);与治疗前相比,治疗组与对照组治疗后反流症状指数、反流体征指数降低(P<0.01),但治疗组优于对照组(P<0.05)。结论贝母瓜蒌散联合奥美拉唑治疗反流性咽喉炎能有效降低反流症状指数及反流体征指数,改善临床症状。
Objective To explore the clinical efficacy of terms of snakegourd fruit powder combined omeprazole in the treatment of reflux laryngitis. Methods The 120 patients with reflux laryngitis were randomly divided into joint group and control group,60 cases in each group. The control group patients were treated with Omeprazole Enteric-coated Tablets（ PPI） and Mosapride Citrate（ Promoting gastric dynamics medicine）,and the joint group patients were treated with traditional Chinese medicine fritillaria snakegourd fruit powder based on the control group. The treatment effect,reflux symptom index and reflux index signs of two groups of patients are compared. Results The total efficiency of joint group after treatment is 88. 3%,which is significantly higher than the control group（ 58. 3%）,the difference was statistically significant（ P〈0. 05）; Compared with control group,the effective rate of the joint group patients after treatment is higher and the inefficiency is llower,the difference was statistically significant（ P〈0. 05）. Compared with the treatment before,the reflux symptom index and reflux index signs of joint group and control group patients after treatment are reduced,the difference was statistically significant（ P〈0. 05）; Compared with the control group,the reflux symptoms index and signs of the joint group patients after treatment are lower,the difference was statistically significant（ P〈0. 01）.Conclusion Terms of snakegourd fruit powder combined omeprazole in treatment of reflux laryngitis has better clinical curative effect,which is worth popularizing in clinic.
出处
《长春中医药大学学报》
2015年第4期759-761,共3页
Journal of Changchun University of Chinese Medicine
基金
北京市中医药科技项目(JJ2005-22)
