摘要
目的观察中西医结合治疗膝骨关节炎的临床效果及安全性。方法选取膝骨关节炎患者80例,随机分为观察组与对照组,各40例,观察组采用透明质酸钠注射液关节腔内注射联合止骨增生丸口服治疗,对照组仅行透明质酸钠注射液关节腔内注射治疗,连续治疗5周,对比2组治疗前、后膝关节功能改善、临床疗效及不良反应发生情况。结果 2组治疗前Lysholm膝关节各项评分比较无统计学意义(P>0.05),治疗后各项评分均较治疗前显著下降(P<0.05);观察组治疗后Lysholm膝关节各评分均显著低于对照组(P<0.05);观察组总有效率92.5%,高于对照组的55.0%(P<0.05);2组治疗过程中均未发生明显不良反应。结论透明质酸钠注射液关节腔内注射联合止骨增生丸口服治疗,可有效缓解膝骨关节炎患者疼痛症状,改善其膝关节功能,且无明显不良反应。
Objective To observe the clinical efficacy of the combination of Chinese traditional and western medicine in treating knee osteoarthritis and its safety. Methods A total of 80 knee osteoarthritis patients who were admitted in our hospital were included in our study and randomized into the observation group and the control group with 40 cases in each group. The patients in the observation group were given intra-articular injection of sodium hyaluronate and born hyperplasia pills for oral use. The patients in the control group were only given intra-articular injection of sodium hyaluronate. They were continuously treated for five weeks. The improvement of knee joint function,the clinical efficacy,and the occurrence of adverse reactions before and after treatment in the two groups were compared. Results The comparison of the various scores of Lysholm knee joint function before treatment between the two groups was not statistically different（ P〈0. 05）. The various scores after treatment were significantly reduced when compared with those before treatment（ P〈0. 05）. The various scores of Lysholm knee joint function after treatment in the observation group was significantly lower than those in the control group（ P〈0. 05）. The total effective rate in the observation group was significantly higher than that in the control group（ P〈0. 05）. No adverse reactions occurred during the therapeutic process in the two groups. Conclusion The intra-articular injection of sodium hyaluronate in combined with oral use of born hyperplasia pills can effectively relieve the pain and improve the knee joint function with a definite efficacy and no obvious adverse reactions.
出处
《长春中医药大学学报》
2015年第4期796-798,共3页
Journal of Changchun University of Chinese Medicine
基金
北京军区医疗成果项目(2009229)
关键词
透明质酸钠
止骨增生丸
膝骨关节炎
sodium hyaluronate
born hyperplasia pills
knee osteoarthritis
