摘要
目的分析胎儿颈项透明层(NT)值与羊水细胞染色体核型分析的关系。方法对我院孕11~13+6周的1000例孕妇给予超声检查NT值,并对有必行产前介入性诊断的孕妇给予羊水染色体核型分析。根据超声检查结果分为增厚组(NT≥2.5 mm)和正常组(NT〈2.5 mm),每组各500名患者。计算异常染色体比例及类型。结果增厚组检出异常染色体共97例,正常组无异常染色体者,两组比较差异有统计学意义(P〈0.05)。结论胎儿NT值较高者,其发生羊水细胞染色体核型的异常比例也较高,此研究有助于筛查胎儿染色体的异常情况。
Objective To analyze the relationship between nuchal translucency (NT) value and chromosomal karyotype analysis of amniotic cell. Methods Supersonic inspections were provided for 1000 cases women who were be pregnant for 11 to 13 weeks for extending 6 weeks to obtain NT values.Those pregnant women who had the need for prenatal in-terventional diagnosis were dealt with chromosomal karyotype analysis of amniotic cells.They were divided into thicking group (NT≥2.5 mm) and control group (NT〈2.5 mm) according to the results of the ultrasonic, each group had 500 cases. The proportion and type of abnormal chromosomes were calculated. Results The abnormal chromosome was detected in 97 cases in thickening group and was 0 in control group.After comparison,there was a statistical difference in both group (P〈0.05). Conclusion If the NT value is higher,the occurrence of proportion of abnormal chromosome karyotype of amniotic cells is also high,which is beneficial for screening chromosomal abnormalities in fetus.
出处
《中国当代医药》
2015年第22期99-101,共3页
China Modern Medicine
基金
广东省惠州市科技计划项目(20140810)
关键词
颈项透明层
羊水细胞
染色体核型异常
Nuchal translucency
Amniotic cell
Chromosomal karyotype abnormality