摘要
我国海域辽阔,可开发利用的生物资源极其丰富,海洋生物中含有许多结构新颖、活性显著的天然化合物,引起了科研工作者的广泛关注。甾体化合物广泛存在于多种海洋生物体内,它们具有抗肿瘤、抗菌、抗炎和抗病毒等诸多生物活性,现对海洋甾体化合物分离纯化、生物来源、结构特征和生物活性的研究进展加以概述,以期为海洋药物开发提供参考。
With marine species being abundant, the sea offers enormous resources for structurally diverse nat-ural compounds with various beneficial biological activities. Therefore, increasing knowledge on novel functional ingredients with biological activities from marine organisms has been gained much attention. Marine organisms have proven to be a rich source of sterols. Additionally, sterols have been suggested to have anticancer, anti- inflammatory, antibacterial and antiviral activities. This article focuses on purification methods, biogenetic derivation, chemical construction and biological activity of sterols in order to provide reference for marine medicinal development.
出处
《福建水产》
2015年第4期325-337,共13页
Journal of Fujian Fisheries
基金
省属公益类科研院所基本科研专项(闽科计[2014]60号)
厦门市海洋经济发展专项(14CZP041HJ15)
关键词
甾体化合物
化学结构
生物活性
sterols
chemical construction
biological activity
