摘要
目的探讨吡格列酮与二甲双胍在治疗2型糖尿病中的临床效果。方法选取2型糖尿病患者70例,按随机数字表法分为对照组、观察组各35例,对照组采用二甲双胍治疗,观察组采用二甲双胍联合吡格列酮治疗,对比两组患者治疗效果及不良反应发生情况。结果两组患者治疗后2 h PG、FPG、Hb A1C指标均改善,但观察组治疗后2 h PG、FPG、Hb A1C等指标改善情况优于对照组(P<0.05);两组不良反应发生率差异无统计学意义(P>0.05)。结论吡格列酮与二甲双胍联合应用在治疗2型糖尿病中安全有效。
Objective To investigate the clinical efficacy of pioglitazone and metformin in patients with type 2 diabetes.Methods70 cases of type 2 diabetic patients were randomly divided into control group,observation group 35 cases,control group received metformin treatment,observation group metformin combined with pioglitazone treatment,compared to the treatment groups of patients and adverse events happening.ResultsThe two groups of patients after treatment 2 h PG,FPG,HbA1C indicators were significantly improved,but the observation group 2hPG,FPG,HbA1C and other indicators to improve the situation than the control group（P〈 0.05）,the incidence of adverse reactions was no significant difference in comparison（P〉 0.05）.Conclusion Pioglitazone and metformin in the treatment of type 2 diabetes in effect safe and effective,with application value.
出处
《中国卫生标准管理》
2015年第20期103-104,共2页
China Health Standard Management
