摘要
目的：对比卡介菌多糖核酸与醋酸曲安奈德治疗口腔扁平苔藓的疗效。方法选取我院2012年4月～2013年12月收治的口腔扁平苔藓患者251例作为研究对象，将其随机分为实验组126例和对照组125例。对照组给予醋酸曲安奈德注射液治疗，实验组给予卡介菌多糖核酸进行局部注射治疗，治疗2个疗程后观察两组患者的疗效。结果实验组患者总有效率为95.24%，显著高于对照组患者的76.80%，差异有统计学意义（P＜0.05）。结论卡介菌多糖核酸局部注射治疗口腔扁平苔藓能够快速缓解患者的临床症状，疗效较卡介菌多糖核酸显著，且半衰期长，停药后复发率低，患者的毒副反应发生率低，值得在临床上推广与应用。
Objective Comparison of BCG polysaccharide nucleic acid triamcinolone acetonide acetate and curative effect for the treatment of oral cavity compressed moss.methods Selected from April 2012 to December 2013 were 251 cases of patients with oral squamous moss as the research object, the 126 cases were randomly divided into experimental group and control group （n=125）. Control group given triamcinolone acetonide acetate injection treatment, the experimental group given local injection of BCG polysaccharide nucleic acid treatment, after 2 courses of treatment to observe the curative effect of two groups of patients.Results Experimental group total effective rate was 95.24%, signiifcantly higher than the control group 76.80% of the patients, the difference was statistically significant （P〈0.05）.Conclusion Local injection of BCG polysaccharide nucleic acid treatment of oral cavity compressed moss can quickly relieve the patient＇s clinical symptoms, clinical effectiveness of BCG polysaccharide nucleic acid signiifcantly, and long half-life, low recurrence rate after the drug was stopped, the incidence of adverse reaction of patients with low, is worthy of popularization and application in clinic.
出处
《全科口腔医学电子杂志》
2015年第4期99-100,共2页
Electronic Journal of General Stomatology
关键词
口腔扁平苔藓
醋酸曲安奈德
卡介菌多糖核酸
Oral squamous moss
Triamcinolone acetonide acetate
BCG polysaccharide nucleic acid
