摘要
目的:探讨应用雷贝拉唑联用呋喃唑酮、克拉霉素治疗Hp相关性消化性溃疡的治疗效果。方法:选取2013年6月-2014年6月笔者所在医院收治的78例Hp相关性消化性溃疡患者,按照随机数字表法分为对照组和观察组,每组39例。对照组给予单用奥美拉唑治疗,观察组给予雷贝拉唑联用呋喃唑酮、克拉霉素治疗,对两组临床疗效进行比较。结果:观察组治疗总有效率94.87%,对照组为79.49%,差异有统计学意义(P<0.05);经实验室检查,观察组中有35例已根除Hp,根除率为89.74%;对照组中有27例根除Hp,根除率为69.23%,差异有统计学意义(P<0.05)。结论:应用雷贝拉唑联用呋喃唑酮克拉霉素治疗Hp相关性消化性溃疡,效果明显、Hp根除率高,有着重要的临床参考意义。
Objective： To evaluate the therapeutic effect of using furazolidone combined with rabeprazole, clarithremycin in treating Hp-related peptic ulcer. Method： 78 cases of patiens with Hp related peptic ulcer from june 2013 to june 2014 were selected, they were randomly divided into control group and observation group, 39 cases in each group. Control group were treated with omeprazole, observation group were given rabeprazole combined with furazolidone and ciarithromycin treatment, and then the total treatment efficiency of the two groups were compared.Result： In the observation group given furazolidone combined with rabeprazole elarithromycin therapy, the total treatment effective rate was 94.87%; in control group of patients given a single treatment with omeprazale, the total effective rate was 79.49%. Difference between groups was statistically significant （P〈0.05） ; after laboratory tests, among patients in the experimental group, 35 patients have been eradicated Hp, eradication rate was 89.74%; in control group, 27 patients were eradicated Hp, eradication rate was 69.23%, difference between groups was statistically significant （P〈0.05）.Concluslon： Rabeprazole combined with clarithromycin furazolidone in treating Hp related peptic ulcer, the effect is obvious, and the Hp eradication rate was high, which has important clinical reference significance.
出处
《中外医学研究》
2015年第23期57-58,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
