摘要
目的评价"冬病夏治"三伏贴预防冠心病患者冬季心绞痛发作、中医证候的临床疗效,分析贴敷有效证型及影响发生冬季再住院事件的因素。方法采用前瞻性队列研究,收集符合纳入标准的冠心病患者230例,根据患者意愿是否进行贴敷分为贴敷组(116例)和对照组(114例)。半年后随访,进行统计分析。结果贴敷组冬季心绞痛发作、中医证候疗效改善优于对照组,阳虚寒凝证患者的贴敷疗效优于非阳虚寒凝证患者,差异具有统计学意义(P<0.05);三伏贴是发生冬季因心绞痛再住院事件的保护因素[P<0.01,RR=0.029,95%CI(0.003,0.312)]。结论 "冬病夏治"三伏贴是预防冠心病心绞痛冬季发作的有效方法,不良反应较少,患者满意度较高,值得进一步采用多中心随机对照试验加以验证。
Objective To evaluate the effect of Dog - days paste treating winter diseases in summer for prevention and treatment of angina pectoris. Methods This was a prospective cohort study which collected 230 patients with angina pectoris met the inclusion criteria. According to the patient＇ s will, 116 cases was divided into the treatment group and the other 114 as control group, follow - up for half a year for statistical analysis. Results The effects of angina pectoris attacks and TCM symptoms in sticking group was sig- nificantly improved compared with the control group. In sticking group, patients with syndrome of yang deficiency and cold coagulated improvement were better than those who without yang deficiency and cold coagulation syndrome in terms ot syndrome curative effect. The difference was statistically significant（ P 〈0. 05）. Dog - days paste was a influencing factor in hospitalized events in win- ter[ P 〈0. 01, RR = 0. 029,95% CI （0. 003,0. 312）]. Conclusion This study has preliminarily verified Dog - days paste is the ef- fective method for prevention of angina pectoris of winter attack. The masses have higher satisfaction and good security on Dog - days paste. It is worth further to verify by multi center randomized controlled trials.
出处
《中西医结合心脑血管病杂志》
2015年第9期1086-1089,共4页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金
名老中医独特辨证方法传承研究(No.2013BAI13B01)
关键词
冠心病
心绞痛
冬病夏治
三伏贴
angina pectoris
Dog- days paste
treating winter diseases in summer
