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四肢躯干侵袭性纤维瘤13例临床分析

Clinical analysis of 13 cases aggressive fibromatosis on limbs and trunk
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摘要 目的研究四肢关节侵袭性纤维瘤的诊断治疗方法。方法通过2010年1月~2014年12月我院收治13例四肢躯干侵袭性纤维瘤患者病例报道,总结该病治疗经验。结果中青年女性占全部患者比例53.84%,乳腺发病率23.07%,根据术后按照Enneking肿瘤分期,良性肿瘤10例,低度恶性3例;随访过程中,局部复发率为7.69%。结论四肢躯干部位侵袭性纤维瘤多发于乳腺及肌肉、肌腱丰富部位,青年女性好发,局部侵袭性生长,但不发生转移的肿瘤,临床诊断主要以病理形态学为依据,治疗方法主要以手术局部扩大切除为主,复发因素多于肿瘤体积、低度恶性程度及手术中是否做到切缘阴性有关,预后较好。 Objective To summarize the diagnosis and treatment of aggressive fibromatosis on limbs and trunk. Methods All 13 cases of aggressive fibromatosis were reported to summarize the experience of treatment during January 2010 to December 2014. Results The proportion of middle and young female was 53.84% in all cases. The incidence of breast was 23.07%. According to Enneking staging of tumor, 10 cases were benign and 3 cases were low malignant potential. The recurrence rate was 7.69% during the follow-up. Conclusion The breast and the part which is plenti- ful of muscle and tendon in young-aged women are susceptible to the aggressive fibromatosis. Local invasive growth and no metastasis is the basic characteristic of the aggressive fibromatosis. Clinical diagnosis is mainly depended on pathological test. The extended resection is effective treatment.The recurrence rate is related to the volume of tumor, malignant potential and whether the margin of extended resection is clean.The prognosis is good.
出处 《中国现代医生》 2015年第20期47-50,共4页 China Modern Doctor
关键词 肿瘤 侵袭性纤维瘤 诊断 治疗 Tumor Aggressive fibromatosis Diagnosis Treatment
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参考文献17

  • 1Mendenhall WM,Zlotecki RA,Morris CG,et al. Aggressive fibromatosis[J]. Am J Clinoncol, 2005,28 (2) : 211-215.
  • 2Gronchi A, Casali PG, Mariani L, et al. Quality of surgery and outcome in extra-abdominal aggressive fibromatosis: A series of patients surgically treated at a single institution[J]. J Clinoncol, 2003,21 (7) : 1390-1397.
  • 3刘源,李甲振,张岩,卢新昌,石海龙,张鹏飞,徐宗潮.四肢侵袭性纤维瘤病的治疗体会[J].肿瘤基础与临床,2014,27(3):240-242. 被引量:2
  • 4林庆衍,白冬雨.侵袭性纤维瘤病恶变为纤维肉瘤1例[J].临床肿瘤学杂志,2007,12(6):478-479. 被引量:10
  • 5Collins BJ,Fischer AC,Tufaro AP, et al. Desmoid tumors of the head and neck[J]. Am Plast Surg,2005,54(1):103- 108.
  • 6Colombo C,Miceli R,Lazar AJ,et al. CTNNB1 45F muta- tion is a molecular prognosticator of increased postopera- tive primary desmoid tumor recurrence:An independent, multicenter validation study[J]. Cancer, 2013,119 : 3696- 3702.
  • 7Romero S, Szafranska J, Cabrera E, et al. Role of tumor- associated macrophages and angiogenesis in desmoid-type fibromatosis[J]. Virchows Arch, 2012,461 : 117-122.
  • 8袁志平,宋永文,李晔雄.侵袭性纤维瘤病诊治进展[J].肿瘤学杂志,2008,14(3):236-239. 被引量:25
  • 9Leithner A, Gapp M,Radl R,et al. Immunohistochemical analysis of desmoid tumours[J]. J Clin Pathol,2005,58 (11):1152-1156.
  • 10Lira CL,Walker MJ,Mehta RR,et al. Estrogen and antie- strogen binding sites in desmoid tumors[J]. Eur J Cancer Clin Oncol, 1986,22(5) : 583- 587.

二级参考文献52

  • 1陈冉,徐德龙,杨庆军.胸壁侵袭性纤维瘤病1例报道[J].罕少疾病杂志,2000,7(3):45-45. 被引量:1
  • 2Juan Rosai,回允中.外科病理学(第9版)[M].北京:北京大学医学出版社,2006.2249-2252.
  • 3Kobayashi H,Kotoura Y,Hosono M,et al.MRI and scintigraphic features of extraabdominal desmoidtumors[J].Clin Imaging,1997,21:35-39.
  • 4Romero JA,Kim EE,Kim CG,et al.Different biologic features of desmoid tumors in adult and juvenile patients:MR demonstration[J].J Comput Assist Tomogr,1995,19:782-787.
  • 5Abdelkader M,Riad M,Williams A,et al.Aggressive fibromatosis of the head and neck[J].J Laryngol Otol,2001,115(10):772-776.
  • 6Wang CP, Chang YL, Ko JY, et al. Desmoid tumor of the head and neck[J]. Head Neck, 2006, 28(11):1008-1013.
  • 7Goy BW, Lee SP, Eilber F, et al. The role of adjuvant radiotherapy in the treatment of resectable desmoid tumors [J]. Int J Radiat Oncol Biol Phys, 1997, 39(3):659-665.
  • 8Caspari R, Olschwang S, Friedl W, et al. Familial adenomatous polyposis: desmoid tumours and lack of ophthalmic lesions (CHRPE) associated with APC mutations beyond codon 1444[J]. Hum Mol Genet, 1995, 4(3): 337-340.
  • 9Friedl W, Caspari R, Sengteller M, et al. Can APC mutation analysis contribute to therapeutic decisions in familial adenomatous polyposis? Experience from 680 FAP families[J]. Gut, 2001, 48(4):515-521.
  • 10Wilcken N, Tattersall MH. Endocrine therapy for desmoid tumors[J]. Cancer, 1991, 68(6): 1384-1388.

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