摘要
目的：观察葛根素注射液对小儿重症肺炎肺表面活性蛋白及炎性介质的影响情况。方法：选取2013年2月~2015年1月诊治的60例重症肺炎小儿为研究对象,将其随机分为对照组（常规治疗组）30例和观察组（常规治疗加葛根素注射液组）30例,然后将两组患儿治疗前和治疗后不同时间的血清肺表面活性蛋白及炎性介质指标水平进行分别检测及比较。结果：观察组治疗后3d、5d及10d的血清肺炎肺表面活性蛋白及炎性介质指标水平均明显低于对照组（P均〈0.05）。结论：葛根素注射液对小儿重症肺炎肺表面活性蛋白及炎性介质的影响较大,可有效改善此类患儿的疾病状态。
Objective：To study the influence situation of puerarin injection on the pulmonary surfactant protein and inflammatory mediators of children with severe pneumonia.Methods：A total of 60 children with severe pneumonia in our hospital from February 2013 to January 2015 were selected as study object,and they were randomly divided into control group（routine treatment group）and observation group（routine treatment and puerarin injection group）by half.Then the serum pulmonary surfactant protein and inflammatory mediators of two groups before the treatment and at different time after the treatment were respectively detected and compared.Results：The serum ulmonary surfactant protein and inflammatory mediators of observation group on the third,fifth and tenth day after the treatment were all significantly lower than those of control group（P〈0.05）.Conclusion：Puerarin injection has satisfactory effect on the pulmonary surfactant protein and inflammatory mediators of children with severe pneumonia,and it can effectively improve the disease state of children with severe pneumonia.
出处
《海南医学院学报》
CAS
2015年第9期1259-1261,共3页
Journal of Hainan Medical University
基金
河北省卫生厅资助基金(hb281223)~~
关键词
葛根素注射液
重症肺炎
肺表面活性蛋白
炎性介质
儿童
Puerarin injection Children with severe pneumonia Pulmonary surfactant protein Inflammatory mediators
