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肿瘤标志物和生化指标在消化道肿瘤转移中的临床意义 被引量:5

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摘要 目的:分析研究肿瘤标志物和生化指标在消化道肿瘤转移中的临床意义。方法:选取2010年2月-2014年1月我院接收的消化道肿瘤患者120例,采用罗氏411电化学发光全自动免疫分析仪,另外,抽取同一时期消化道良性疾病患者50例,测定CA242(血清糖类抗原)、CA125(糖类抗原)、AFP(甲胎蛋白)、CEA(癌胚抗原)以及CY-211(细胞角蛋白19)含量,分析研究临床诊断的灵敏度以及特异度。结果:多种瘤标志物联合检查对消化道肿瘤的临床诊断灵敏度明显要比各个指标单独检测高(P〈0.05);胃癌、结直肠癌以及肝癌患者血清CA242(血清糖类抗原)、CA125(糖类抗原)、AFP(甲胎蛋白)、CEA(癌胚抗原)以及CY-211(细胞角蛋白19)含量明显要比消化道良性疾病高(P〈0.05)。结论:消化道肿瘤采取多肿瘤标志物检测,可以使临床诊断灵敏度明显提高,适用于肿瘤高危人群以及健康人群的筛选检查,同时对预后以及治疗效果给予有效判断,具有临床推广价值。
出处 《北方药学》 2015年第9期118-119,共2页 Journal of North Pharmacy
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