摘要
目的分析老年社区获得性肺炎(CAP)病原菌分布及耐药情况。方法回顾性分析临海市中医院2012年1月至2013年12月收治的463例老年CAP患者的病原菌分布及药敏情况;统计分析采用SPSS17.0进行分析,不同组间的比较采用χ2检验;CAP判断依据2006年中华医学会呼吸病学分会于制定的CAP诊断标准。结果 463例老年CAP患者痰培养阳性402例(86.83%),共获得病原菌459株,革兰阴性杆菌占64.27%、革兰阳性球菌占26.36%、真菌占5.88%、非典型病原菌占3.49%。药敏试验显示:主要革兰阴性杆菌对常用抗菌药物的耐药性差异有统计学意义(P<0.05),肺炎链球菌与金黄色葡萄球菌对环丙沙星、左氧氟沙星耐药性差异有统计学意义(P<0.05)。结论老年社区CAP感染的病原菌以革兰阴性杆菌为多见,所分离的病原菌呈高度耐药性。
Objective To analyze the pathogens and drug resistance of community acquired pneumonia（CAP）among seniors. Methods A retrospective study was conducted to analyze the pathogenic features and drug resistance of CAP among 463 senior patients hospitalized from January 2012 to December 2013.The diagnosis of CPA was based on the Chinese medical association respiratory CAP diagnostic criteria in 2006.Chi-square test was used for statistical analysis. Results There were 402patients（86.82%）whose sputum cultures were positive and a total 459 strains of pathogens were isolated,including 64.27% of Gram negative bacteria,26.36% of Gram positive bacteria,5.88% of fungi and 3.49% of atypical pathogens.Drug sensitivity test revealed that the difference of resistance of gram negative bacilli to common used antibiotics were significant（P〈0.05）.Streptococcus pneumoniae and Staphylococcus aureus were resistant differently to ciprofloxacin and levofloxacin（P〈0.05）. Conclusions Gram-negative bacilli is a major pathogen of senior CAP and is highly resistant to antibiotics.
出处
《中国预防医学杂志》
CAS
2015年第8期624-627,共4页
Chinese Preventive Medicine
基金
台州市科技计划项目(11KY37)
关键词
社区获得性肺炎
病原菌
耐药性
老年人
Community acquired pneumonia
Pathogenic bacteria
Drug resistance
Aged
