摘要
目的:分析TORCH的检验结果,探讨TORCH感染对于自然流产患者的影响。方法:选取2010年1月到2013年12月来南京市第一医院检查的无自然流产史孕妇300例(对照组),并选择同期有自然流产史孕妇300例(观察组),使用ELISA检验法检测所有孕妇TORCH抗体,对比分析两组阳性率。结果:观察组血清中的风疹病毒(RV)、单纯疱疹病毒(HSV-Ⅱ)、巨细胞病毒(CMV)、弓形虫(TOX)的阳性率分别为12.00%、52.00%、27.67%、3.33%,明显高于对照组的2.00%、3.00%、2.67%、1.00%,差异有统计学意义(P<0.05);观察组流产、死胎和早产的比率分别为37.67%、7%、11.67%,明显高于对照组的7.67%、0.33%、0.67%,差异有统计学意义(P<0.05);观察组HSV-Ⅱ和CMV所致不良妊娠发生率分别为58.30%﹑59.04%,与RV、TOX所致不良妊娠发生率66.67%、50.00%比较,差异有统计学意义(P<0.05)。结论:TORCH病原体或者病毒抗体阳性率的孕前检测对于预防自然流产有重要的临床意义。
Objective： To investigate the impact of TORCH infection on patients with spontaneous abortion by analyzing the test results of TORCH. Methods： Choose 300 pregnant women without spontaneous abortion experience as control group,who were examined in Nanjing First Hospital from January 2010 to December 2013;and 300 pregnant women with spontaneous abortion experience as observation group at the same time. The TORCH antibodies of the two groups of pregnant women Were tested by ELISA method, comparing the positive rates of the two groups. Results： The positive rates of RV（12.00%）, HSV- II （52.00%）, CMV（27.67%）, TOX（3.33%） of the observation group were significantly higher than those of RV（2.00%）,HSV- II （3.00%）, CMV（2.67%）, TOX（1.00%） of the control group, the difference was statistically significant （P〈0.05）. The rates of abortion （37.67%）, stillbirth, （7%） and premature （11.67%） in the observation group were significantly higher than those of abortion（7.67%）, stillbirth（0.33%） and premature（0.67%） in the control group, the difference was statistically significant（P〈0.05）. The incidence rates of HSV-II and CMV induced adverse pregnancy in the observation group were 58.30% and 59.04%, and those of RV and TOX ＇induced adverse pregnancy were 66.67% and 50.00%, the difference was statistically significant （P〈0.05）. Conclusion： It is important to test TORCH pathogen or serum virus antibody positive rate before pregnancy for preventing spontaneous abortion.
出处
《现代生物医学进展》
CAS
2015年第19期3707-3710,共4页
Progress in Modern Biomedicine
