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急性ST段抬高性心肌梗死患者低钙血症分析

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摘要 目的探讨ST段抬高且入院后行急诊PCI的急性心肌梗死患者低钙血症的发生及与患者预后的关系。方法ST段抬高急诊行PCI的患者155例,按照入院时血浆钙离子浓度分为非低钙血症组122例(78.71%),低钙血症组33例(21.29%)。比较两组患者一般情况、基础疾病、发病时心率、冠状动脉病变情况、入院时心超EF值、肌钙蛋白、肾功能以及临床远期预后情况。结果低钙血症组糖尿病、高脂血症发生率比非低钙血症组高,差异有统计学意义(P=0.022、0.014),低钙血症组肾功能比非低钙血症组差,差异有统计学意义(P=0.026)。冠状动脉造影显示,低钙血症组患者前壁及广泛前壁心肌梗死发生率比非低钙血症纽高,差异有统计学意义(P=0.044),且单支病变发生率高于非低钙血症组,差异有统计学意义(P=0.00)。两组再发心肌梗死、猝死的心血管事件发生率,差异无统计学意义(P=0.748、0.250、0.854)。结论低钙血症的急性ST段抬高的患者基础疾病较多,肾功能差及单支血管病变严重。 Objective To determine the prevalence and prognostic implication of hypocalcemia in the ST-elevation myocardial infarctionpatients. Methods Restrospective analysis of collected data on 155 PCI-treated STEMI patients 55-80y at The First Affiliated Hospital of Soochow University between January 2014 and October 2014 was performed.A tolal of 155 cases with acute myocardial infarction combined with acute Percutaneous Coronary Intervention were enrolled in the study.155patients were dividedinto two groups according to the plasma calcium concentration : the normal control group 122 ( 78.71% ) and the hypocalcemia group 33 ( 21.29% ) . Data of the general condition, underling diseases, heart rate, coronary disease, left ventricular ejection fraction of admission into hospital, cardiac troponin and longterm progrosis were compared between the two groups and analyzed. Results Patients with hypocalcemia had a significantly higher rate than the control group in diabetes and hyperlipemia ( P=0.022, 0.014 ) . Renal function of the hypercalcimia group is worse than the control group. The results of coronary angiography showed that there were significant differences between the hypocalcemia group and the control group with regard to the percentage of anterior wall myocardial infarction, single coronary lesion in the group hypercardial were significantly higher than the control group.During a follow-up investigation, cardiac events ( heart failure, reinfarction, sudden death ) , the incidence rates of the hypercardial group were also higher than the control group, but there was no significant difference between them ( P=-0.748, 0.250, 0.854 ) . Conclusion The ST-elevation patients with hypocalcamia had a severier underlying diseases, renal disfunction and worse single coronary lesion condition.
出处 《浙江临床医学》 2015年第9期1505-1507,共3页 Zhejiang Clinical Medical Journal
关键词 急性心肌梗死 低钙血症 远期预后 Acute myocardial infarction Hypoealcemia Precordial S-T segment elevation Long-term prognosis
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