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抗着丝粒蛋白B抗体在自身免疫性疾病中的表达及临床意义

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摘要 目的探讨抗着丝粒蛋白B(CENP-B)抗体在自身免疫性疾病中的表达及,临床意义。方法回顾性分析2011年3月至2015年3月抗CENP—B抗体阳性189例患者的临床资料。结果 抗CENP—B抗体阳性见于系统性硬化症(SSc)37.04%、系统性红斑狼疮(SLE)16.04%、干燥综合征(pSS)14.81%、类风湿关节炎(RA)15.34%、局限性硬皮病4.76%、雷诺现象3.7%、重叠综合征和原发性胆汁性肝硬化(PBC)各1.59%、自身免疫性肝病2.65%、CREST综合征和硬化性胆管炎各1.06%。结论.抗CENP-B阳性多见于系统性硬化症患者中,亦见于其他多种自身免疫性疾病中,抗CENP-B阳性患者需结合其它临床资料进一步明确诊断。
出处 《浙江临床医学》 2015年第9期1612-1613,共2页 Zhejiang Clinical Medical Journal
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参考文献6

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二级参考文献13

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