摘要
目的 观察依达拉奉联用奥曲肽治疗急性胰腺炎的临床效果.方法 选取我院2012年5月～2013年5月收治的急性胰腺炎患者78例,随机分为治疗组与对照组各39例,均在常规禁食、胃肠减压、抑酸、补液等治疗的基础上,治疗组加奥曲肽联用依达拉奉治疗,对照组只加用奥曲肽治疗,疗程均为7天,比较两组患者的临床疗效及血清细胞因子水平.结果 治疗组总有效率（94.9％）明显优于对照组（74.3％）,组间差异有统计学意义（P=0.012）;治疗后细胞因子水平与对照组相比均有降低,但治疗组下降更为显著,组间差异有统计学意义（P＜0.05）.结论 在急性胰腺炎患者的临床治疗中,依达拉奉联用奥曲肽可提高患者总有效率,减轻急性胰腺炎的炎症损伤,具有推广应用价值.
Objective To investigate the clinical effects of edaravone combined with octreotid for acute pancreatitis. Methods 78 patients with acute pancreatitis 3 were included in our study. Patients with acute pancreatitis were randomized into two parallel groups： a control group （n=39）, a treatment group （n=39） in which treated with edaravonein addition to octreotid. The clinical effects and serum levels of cytological parameters were measured were observed. Resuits edaravone improved the clinical effects. The levels of cytological parameters were markedly decreased （P〈0.05）. Conclusions Our study suggests thatedaravone combined with octreotid can improve the recovery rate of patients with acute pancreatitis and reduce inflammation injury of oxygen free radicals（OFRs）.
出处
《西部医学》
2015年第9期1399-1402,共4页
Medical Journal of West China
关键词
奥曲肽
依达拉奉
急性胰腺炎
炎症损伤
Edaravone
Octreotid
Acute pancreatitis
Inflammation injur
