摘要
目的探讨丹红注射液联合氢氯噻嗪治疗更年期妇女心律失常的效果。方法选择更年期妇女心律失常患者96例,随机分为治疗组与对照组各48例,对照组给予氢氯噻嗪治疗,治疗组给予丹红注射液联合氢氯噻嗪治疗,疗程均为两个月,观察比较两组的疗效、症状改善及不良反应情况。结果与对照组相比,治疗后治疗组的有效率为97.9%,明显高于对照组(87.5%)(P<0.05)。治疗后两组的中医症状评分明显降低,而治疗组更明显低于对照组(P<0.05)。与治疗前对比,治疗后两组的LVDd值明显减少,而LVEF值明显增加(P<0.05),且治疗组的改善均显著大于对照组(P<0.05)。治疗期间两组的不良反应总体发生情况无统计学差异(P>0.05)。结论丹红注射液联合氢氯噻嗪治疗更年期妇女心律失常,能有效缓解临床症状,改善心功能,从而提高治疗疗效,安全性也比较好,值得推广应用。
Objective To discuss the efficacy of Danhong injection combined with hydrochlorothiazide on arrhythmia of climacteric women.Methods 96 climacteric women with arrhythmia were selected and equally divided into the treatment group and control group. The control group was given the treatment with hydrochlorothiazide, while the treatment group was treated with Danhong injection combined with hydrochlorothiazide. Both course of treatment was two months. Observation was made in the curative effects, improvement of symptoms, and adverse reactions between the two groups. Results Compared with the effective rate of the control group （87.5%）, that of the treatment group was 97.9% which was significantly higher （P 〈 0.05）. After the treatment, the TCM symptom scores of both groups significantly decreased, while those of the treatment were significantly lower （P 〈 0.05）. The LYDd values after treatment in both groups significantly increased compared with those before the treatment, while the LVEF values significantly decreased（P 〈 0.05）. The improvement in the treatment group were more significant than that in the control group（P 〈 0.05）. During the treatment, there was no significant difference in the general incidence of adverse reactions between the two groups （P 〉 0.05）. Cnclusion Danhong injection combined with hydrochlorothiazide on climacteric women with arrhythmias can effectively relieve clinical symptoms and improve heart function, thereby enhance the therapeutic efficacy with good safety. It is worthwhile to be promoted.
出处
《西南国防医药》
CAS
2015年第9期964-967,共4页
Medical Journal of National Defending Forces in Southwest China
关键词
更年期
妇女
丹红注射液
氢氯噻嗪
心律失常
疗效
climacteric
woman
Danhong injection
hydrochlorothiazide
arrhythmia
efficacy
