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子宫内膜浆液性腺癌51例临床病理分析 被引量：8

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摘要 目的分析子宫内膜浆液性腺癌(USC)的临床病理特点。方法系统回顾本院收治的51例USC和同期子宫内膜样腺癌974例患者的临床资料。结果 1USC的发病率为4.0%,其与子宫内膜样腺癌的发病平均年龄分别为57.2岁和51.3岁,两者相比较,差异有显著性(P<0.05);2糖尿病及高血压的发生率均低于子宫内膜样腺癌,差异有显著性(P<0.05),说明肥胖是两者共同的发病高危因素;3USC中早期患者(Ⅰ期+Ⅱ期)29例(60.4%),晚期患者(Ⅲ期+Ⅳ期)19例(39.6%),子宫内膜样腺癌中早期患者769例(83.2%),晚期患者155例(16.8%),差异有显著性(P<0.05);51例USC患者中,3例行根治性放疗,48例经手术治疗,术后单纯化疗25例,单纯放疗8例,化疗+放疗15例。48例手术患者中,合并盆腔淋巴结转移为10例(31.2%)、浸润肌层<1/2的31例(64.6%)、浸润肌层≥1/2的17例(35.4%),脉管间隙受侵9例(18.8%)。其中盆腔淋巴结转移率、肌层浸润情况、脉管间隙受侵率三个指标,与子宫内膜样腺癌比较,差异有显著性(P<0.05);4USC的5年生存率为43.1%,子宫内膜样腺癌的5年生存率为73.9%,差异有显著性(P<0.01)。结论 USC发病率低,发病年龄较子宫内膜样腺癌大,肥胖可能是两者共同的发病高危因素。USC的盆腔淋巴结转移率、肌层浸润率、脉管间隙受侵率均高于子宫内膜样腺癌,预后较差。临床上强调早期发现的重要性,合适的治疗方式尚需进一步研究。
作者 刘婷婷 孔为民
机构地区 首都医科大学附属北京妇产医院妇瘤科
出处 《中国临床医生杂志》 2015年第9期74-77,共4页 Chinese Journal For Clinicians
关键词 子宫内膜癌 浆液性癌 病理 预后
分类号 R737.33 [医药卫生—肿瘤]
  • 相关文献

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共引文献13

同被引文献71

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引证文献8

二级引证文献56

中国临床医生杂志
2015年 第9期

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