摘要
目的探讨老年冠状动脉临界病变血管内超声斑块影像学特征与血清高敏C反应蛋(hs-CRP)的关系。方法选择慢性稳定性心绞痛患者97例,男性40例,女性57例,均行冠状动脉造影,冠状动脉临界病变予以血管内超声检查,评估斑块性质,检测血清hs-CRP,对患者冠状动脉临界病变超声特征行进行分析。结果男性较女性患者平均年龄高[(66.5±9.9)岁vs(62.8±10.9)岁],斑块负荷低[(62.20±8.60)%vs(67.30±10.10)%];男女性纤维成分最多[(55.18±13.13)%vs(58.30%±10.39)%];钙化成分最少[5.64±5.61 vs 4.86±3.73]。男女性血清hs-CRP为(8.5±10.1)mg/L和(6.5±6.4)mg/L。斑块纤维成分、纤维脂质、坏死成分和钙化成分均与hs-CRP无相关性。结论慢性稳定性心绞痛患者冠状动脉临界病变时,hs-CRP与冠状动脉斑块性质无相关性。
Objective To study the relationship between the serum level of hs-CRP and the nature of coronary atherosclerotic plaques in elderly patients with CHD. Methods Ninety-seven patients with chronic stable angina pectoris （40 males and 57 females） were included in this study. The na- ture of their coronary atherosclerotic plaques was assessed by coronary arteriography. Their ser- um hs-CRP levels were measured. The relationship between the serum level of hs-CRP and the na- ture of coronary atherosclerotic plaques was studied. Results The mean age of males and females was 66.5~9.9 years and 62.8±10.9 years,the mean plaque burden was 62.20%±8.60% and 67.30%±10. 10%, the maximal fibrotic composition accounted for 55. 18% ± 13. 13% and 58.30%±10.39% ,the minimal calcified composition accounted for 21.2%±13.8% and 24.6%± 12.45%. The serum hs-CRP level was 8.5±10.1 mg/L in males and 6.5±6.4 mg/L in females. The fibrotic plaque compositin,fibrotic fatty,necrotic and calcified compositions were not related with the serum hs-CRP level. Conclusion The serum hs-CRP level is not related with the nature of coronary atherosclerotic plaques in patients with chronic stable angina pectoris.
出处
《中华老年心脑血管病杂志》
CAS
2015年第9期936-938,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词
冠心病
超声检查
介入性
C反应蛋白质
心绞痛
coronary disease
ultrasonography, interventional
C-reactive protein
angina pectoris
