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ERp29在卵巢上皮性肿瘤中的表达及意义 被引量:1

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摘要 目的:研究内质网分子伴侣29(ERp29)在卵巢上皮性肿瘤中的表达及意义。方法:应用组织芯片技术与免疫组织化学染色相结合的方法检测90例卵巢癌组织,60例交界性卵巢肿瘤组织和30例卵巢良性肿瘤组织中ERp29的表达。结果:ERp29在卵巢癌中的阳性表达率为43.33%,低于良性肿瘤和交界性肿瘤的86.67%和73.33%,差异具有统计学意义(P〈0.01),且与肿瘤的临床分期和淋巴结的转移有关(P〈0.05),而与分化程度无关(P〉0.05)。结论:ERp29有可能在卵巢上皮性肿瘤的侵袭和转移中起重要作用,可作为判断卵巢上皮性肿瘤恶性程度和预后的一个良好指标。
出处 《中外女性健康研究》 2015年第16期170-171,共2页 Women's Health Research
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