摘要
目的考察环丙沙星对临床分离的致病菌株的体外抗菌活性。方法采用琼脂二倍稀释法测定环丙沙星对我院临床分离的849株致病菌的MIC及抑菌率。结果环丙沙星对硝酸盐阴性杆菌、哈夫尼亚菌属和淋球菌的抑菌率都达到了100%,对其它致病菌的抑菌率在87.1%-100%。结论环丙沙星对需氧G＋阳性球菌和G-杆菌均具有良好的抗菌作用,可用于治疗临床多种感染性疾病。
Objective Investigate Ciprofloxacin on the separation of pathogenic bacteria pharmacodynamic studies.Methods Minimal Inhibitory Concentrations（ MICs） of Ciprofloxacin were measured using two- fold agar dilution assay. Results Ciprofloxacin on nitrate negative bacilli,Hafnia and Neisseria gonorrhoeae inhibitory rate reached 100%. The sensitive rate of Ciprofloxacin to the other bacterial was 87. 1% - 100%. Conclusion Ciprofloxacin against aerobic G＋cocci and G-bacteria have good antibacterial activity,So,ciprofloxacin can be used for the clinical treatment of a variety of infectious diseases.
出处
《医药论坛杂志》
2015年第9期22-23,共2页
Journal of Medical Forum
基金
郑州市科技局项目(No:CZSYJJ14014)
关键词
环丙沙星
MIC
药效学
体外活性
Ciprofloxacin
MIC
Pharmacokinetic
In vitro activity
