摘要
目的:观察术后应用右美托咪啶和丙泊酚治疗全麻后苏醒期躁动的疗效。方法:选择ASAⅠ或Ⅱ级全麻下行胃癌根治术且术毕出现躁动患者72例,随机分为M组和B组,每组36例。两组术后均用舒芬太尼总量2μg/kg行病人自控静脉镇痛,当苏醒期躁动评分≥2分时,M组静脉泵注右美托咪啶0.75μg/kg,B组静脉泵注丙泊酚1.5mg/kg。观察两组抗躁动起效时间和清醒时间、VAS评分、两组患者的Ramsay镇静评分及副作用。结果:M组和B组镇静深度均在4分以上,抗燥动疗效均达100%。B组比M组起效快,但差异无统计学意义(P>0.05),两组清醒时间比较差异亦无统计学意义(P>0.05);与B组比较,拔管后M组VAS评分明显降低(P<0.05);M组有2例、B组有13例发生循环呼吸抑制,差异有统计学意义(P<0.05);两组患者均未发生恶心呕吐和肌颤。结论:右美托咪啶和丙泊酚均可有效的治疗全麻后苏醒期躁动,右美托咪啶对呼吸循环影响较轻,增加耐受性,更加安全。
Objective： Observation of postoperative application right beauty awakening after mi and propofol anesthesia treatment the curative effect of agitation.Methods： Choose the ASA Ⅰ or Ⅱ level downward and gastric cancer radical surgery during anesthesia bi appear restless,72 cases of patients,randomly divided into M group and B group,36 cases in each group.Two groups were postoperatively with sufentanil total 2μg/kg line of patient controlled intravenous analgesia,when waking period agitation score 2 points or more,group M vein pump note right beautiful mi 0.75μg/kg,group B vein pump injection of propofol 1.5 mg/kg.Observed two groups of agitation effect time and waking time,VAS score,two groups of patients with Ramsay sedation scores,and side effects.Results： M depth of sedation group and B group were at least 4 points,resistance to dry dynamic curative effect was 100%;Grou PB than in group M work fast,but there was no statistically significant difference（P〈0.05）,the waking hours more similar between the two groups has no statistical significance（P〈0.05）;Compared with group B,group M after extubation VAS scores significantly decreased（P〈0.05）;M group 2,group B patients have 13 cases had respiratory depression,the difference was statistically significant（P〈0.05）.Conclusion： Two groups of patients were not occurred nausea and vomiting and muscle tremors.conclusion right the pyrimidine and propofol can effective treatment after general anesthesia to stir,right the pyrimidine has less impact on the respiratory cycle,increase the tolerance,more secure.
出处
《中国医药导刊》
2015年第8期801-802,809,共3页
Chinese Journal of Medicinal Guide
关键词
右美托咪啶
丙泊酚
苏醒期
并发症
Right beautiful Joe pyrimidine
Propofol
Awakening period
Complications
