摘要
AIM: To investigate the efficacy of a novel intraoperative diagnostic technique for patients with preliminary diagnosis of autoimmune pancreatitis(AIP).METHODS: Patients with pancreatic surgery were reviewed to identify those who received a preliminary diagnosis of AIP between January 2010 and January 2014. The following data were collected prospectively for patients with a pathological diagnosis of AIP: clinical and demographic features, radiological and operative findings, treatment procedure, and intraoperative capillary refill time(CRT) in the pancreatic bed.RESULTS: Eight patients(six males, two females; mean age: 51.4 years) met the eligibility criteria of pathologically confirmed diagnosis. The most frequent presenting symptoms were epigastric pain and weight loss. The most commonly conducted preoperative imaging studies were computed tomography and endoscopic retrograde pancreaticodoudenography. The most common intraoperative macroscopic observations were mass formation in the pancreatic head and diffuse hypervascularization in the pancreatic bed. All patients showed decreased CRT(median value: 0.76 s, range: 0.58-1.35). One-half of the patients underwent surgical resection and the other half received medical treatment without any further surgical intervention. CONCLUSION: This preliminary study demonstrates a novel experience with measurement of CRT in the pancreatic bed during the intraoperative evaluation of patients with AIP.
AIM To investigate the efficacy of a novel intraoperativediagnostic technique for patients with preliminarydiagnosis of autoimmune pancreatitis (AIP).METHODS: Patients with pancreatic surgery werereviewed to identify those who received a preliminarydiagnosis of AIP between January 2010 and January2014. The following data were collected prospectivelyfor patients with a pathological diagnosis of AIP: clinicaland demographic features, radiological and operativefindings, treatment procedure, and intraoperativecapillary refill time (CRT) in the pancreatic bed.RESULTS: Eight patients (six males, two females;mean age: 51.4 years) met the eligibility criteria ofpathologically confirmed diagnosis. The most frequentpresenting symptoms were epigastric pain and weightloss. The most commonly conducted preoperativeimaging studies were computed tomography andendoscopic retrograde pancreaticodoudenography. Themost common intraoperative macroscopic observationswere mass formation in the pancreatic head and diffusehypervascularization in the pancreatic bed. All patientsshowed decreased CRT (median value: 0.76 s, range:0.58-1.35). One-half of the patients underwent surgicalresection and the other half received medical treatmentwithout any further surgical intervention.CONCLUSION: This preliminary study demonstratesa novel experience with measurement of CRT in thepancreatic bed during the intraoperative evaluation ofpatients with AIP.