摘要
目的:探讨血塞通对预防糖尿病肾病透析患者动静脉内瘘血栓形成的临床疗效。方法:进行动静脉内瘘术维持性血液透析的糖尿病肾病患者87例随机分为对照组和治疗组,对照组43例,治疗组44例。2组均行动静脉内瘘术,给予常规的术后护理。治疗组于动静脉内瘘术当天开始服用血塞通片。随访12个月,记录内瘘血栓发生、凝血指标及不良反应发生情况。结果:随访12个月,对照组血栓发生率39.5%,治疗组血栓发生率9.1%,2组血栓发生率比较差异有显著性意义(P<0.05)。对照组凝血指标治疗前后无显著性差异,治疗组各凝血指标较治疗前均有显著改善,且与对照组治疗后比较也有明显差异,P<0.05。随访12个月期间,2组均未出现用药不良反应情况。结论:血塞通片用于预防糖尿病肾病透析患者动静脉内瘘血栓形成安全、有效,值得临床推广。
Objective： To investigate the clinical efficacy of Xue-sai-tong tablets, on preventing dynamic fistula thrombosis in patients with diabetic nephropathy in hemodialysis. Methods： 87 cases of diabetic nephropathy in maintenance hemodialysis patients were divided into control group and treatment group. The two groups were arteriovenous fistula operation, nursing routine postoperative. The treatment group was given Xue-sai-tong tablets after arteriovenous fistula operation. After 12 months of follow-up, the incidence of thrombosis, coagulation indexes and adverse reaction were recorded. Results： Follow-up 12 months, the incidence of thrombosis in the control group was 39. 5% , 9. 1% in the treatment group, and there was significant difference （ P 〈 0.05 ） . The coagulation indexes of the treatment group were significantly improved （ P 〈 0. 05 ） . There was no adverse drug reaction recorded during the follow-up period. Conclusion： Xue-sai-tong tablets have an exact effect on preventing dynamic fistula thrombosis in patients with diabetic nephropathy in hemodialysis.
出处
《成都中医药大学学报》
2015年第3期81-83,共3页
Journal of Chengdu University of Traditional Chinese Medicine
关键词
动静脉内瘘
血栓
血塞通片
预防
疗效
Arteriovenous fistula
thrombosis
Xue-sai-tong tablets
prevention
curative effect
