摘要
目的:比较宫颈环形电极切除术(LEEP)与微波治疗慢性宫颈炎的临床疗效。方法:选取134例慢性宫颈炎患者,随机将其分为观察组和对照组,观察组68例,接受LEEP治疗;对照组66例,接受微波治疗;测定治疗前后患者血清肿瘤坏死因子-α(TNF-α)和白细胞介素-6(IL-6)。结果:两组患者轻度慢性宫颈炎的治愈率及总有效率均为100.0%,均无差异;两组患者中度、重度慢性宫颈炎的治愈率及总有效率相比,差异均有统计学意义(x2=14.45,x2=12.43;P<0.05)。观察组术中出血量、术后阴道排液时间分别为(5.1±3.3)ml、(7.9±3.4)d,均显著低于对照组的(11.5±3.2)ml、(15.1±3.5)d,其差异均有统计学意义(t=11.9,t=12.6;P<0.05);观察组术后创面感染发生率、宫颈外翻、宫颈瘢痕率、脱痂出血率以及复发等发生率为0.0%、2.9%、2.9%、2.9%及2.9%,明显低于对照组的6.1%、6.1%、13.6%、15.2%及10.6%,其差异均有统计学意义(x2=11.7,x2=10.8,x2=15.2,x2=15.7,x2=12.3;P<0.05)。两组治疗后患者血清TNF-α和IL-6均明显降低,观察组治疗后患者血清TNF-α和IL-6明显低于对照组,差异均有统计学意义(P<0.01)。结论:LEEP用于中度、重度糜烂的慢性宫颈炎,其疗效确切,不良反应小,具有较好的临床应用价值。
Objective：To compare the effects of Leep knife and microwave on patients with chronic cervicitis. Methods： One hundred and thirty-four patients with chronic cervicitis were randomly divided into two groups, the observation group（n=68 cases） received Leep knife and the control group（n=66 cases） were treated through microwave. Tumor necrosis factor-α（TNF-α）and interleukin-6（IL-6） were detected before and after treatment. Results： The cure rate and total efficicities of the mild chronic cervicitis in the two groups were 100.0%, 94.9% and 100.0%, respectively; that of moderate to severe chronic cervicitis in the two groups were 88.5%, 63.0% and 100.0%, 85.2%（x2=14.45,x2=12.43;P〈0.05）. The in-traoperative blood loss and the time of vaginal fluid were（5.1±3.3）ml and （7.9±3.4）d, （11.5±3.2）ml and（15.1±3.5）d in the two groups（t=11.9,t=12.6;P〈0.05）.The incidence of postoperative wound infection, cervical ectropion, cervical scar, exuvial hemorrhage and recurrence were 0.0%, 2.9%, 2.9%, 2.9%, 2.9% in the observation group were lower than those（ 6.1%, 6.1%, 13.6%, 15.2%, 10.6%） in the control group（x2=11.7, x2=10.8,x2=15.2,x2=15.7,x2=12.3;P〈0.05）. The levels of TNF-α and IL-6 decreased after treatment in both groups. There was significant difference between the two groups after treatment（P〈0.01）. Conclusion： Leep knife could make more significant improvement in the inflammatory status of patients with moderate to severe chronic cervicitis.
出处
《中国医学装备》
2015年第9期95-98,共4页
China Medical Equipment
关键词
宫颈炎
宫颈环形电极切除术
微波
Cervfeitis
Loop electrosurgical excision procedure
Microwave
