摘要
【目的】探讨尿微量白蛋白（MAU）、血红细胞比容（HCT）与对比剂肾病（CIN）的相关性。【方法】选择2011年1月至2012年3月本院收治的86例接受冠状动脉造影诊疗的急性心肌梗死（AMI）患者，根据患者冠脉造影术后是否发生 CIN 将其分为 CIN 组（16例）和非 CIN 组（70例）。所有患者均在术前和术后72 h 进行MAU、HCT 和血清肌酐（SCr）水平测定，比较两组患者冠状动脉造影前后上述指标的变化，并应用 Logistic 回归分析评估 MAU、HCT 与 CIN 的相关性。【结果】CIN 组患者的术后72 h MAU 、HCT 水平高于术前，差异均具有统计学意义（均 P ＜0.05）；CIN 组患者的术后72 h MAU 、HCT 水平高于非 CIN 组，差异均具有统计学意义（均P ＜0.05）。应用多因素 Logistic 回归分析，年龄、性别、高血压、糖尿病、高脂血症、吸烟、体质量指数、左室射血分数、造影剂用量与 CIN 无相关性，差异不具有统计学意义（P ＞0.05），术前 MAU、HCT 水平与 CIN 具有显著相关性（P ＜0.05）。【结论】MAU、HCT 与 CIN 的发生具有一定的相关性。
[Objective]To explore the correlation between microalbuminuria （MAU）,hematokrit（HCT）and contrast-induced nephropathy （CIN）.[Methods]We studied 86 consecutive patients with acute myocardial infarc-tion from January 201 1 to March 2012,who had taken coronary angiography.According to the occurrence of CIN, the patients were divided into the CIN group and the non CIN group.All patients were underwent MAU,HCT, SCR level examination before and 72 hours after coronary artery angiography（CAG）.To compare the changes of a-bove indexes before and after coronary artery angiography,and application of Logistic was used to evaluate the correlation between MAU、HCT and CIN.[Results]72 h after operation ,the levels of MAU and HCT in the CIN group were significantly higher than pre-operation,and the differences were statistically significant （P〈 0.05 ）;Multivariate Logistic regression analysis showed that CIN had no correlation with age,sex,hypertension,diabe-tes,hyperlipidemia,smoking,body mass index,left ventricular ejection fraction and contrast agent dosage,the difference was not statistically significant （P〉0.05）;Preoperative HCT,MAU level and CIN were significantly correlated （P 〈0.05）.[Conclusion]MAU and HCT levels may have certain correlation with the incidence of CIN.
出处
《医学临床研究》
CAS
2015年第8期1577-1578,1581,共3页
Journal of Clinical Research
