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高敏C反应蛋白对经皮冠状动脉介入术后发生造影剂肾病相关性分析 被引量:2

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摘要 目的:对经皮冠状动脉介入(PCI)治疗术前高敏C反应蛋白(hs-CRP)水平进行测定,探究其与患者术后发生造影剂肾病相关性。方法选取2011年4月—2013年5月在我院进行 PCI 手术疗的患者120例为实验对象。根据术前 hs-CRP 值分为3组:A 组(hs-CRP <1 mg/L,n =56),B 组(hs-CRP 1~3 mg/L,n =40)和 C 组(hs-CRP >3 mg/L,n =24)。观察各组术后造影剂肾病的发生情况以及探究其两者之间的相关性。结果A、B、C 组患者术后 CIN 的发生率分别为8.93%、22.5%和50.0%,经过统计学比较,差异有统计学意义(P <0.05)。患者术前 hs-CRP 水平年龄在75岁以上、男性、糖尿病、贫血、水化治疗均与 CIN 显著独立相关。C 组 MACE 发生率均高于A 组、B 组(P <0.05)。结论接受 PCI 手术治疗的患者,其术前 hs-CRP 水平与其术后 CIN 的发生具有一定的相关性,患者术前 hs-CRP 水平越高,术后更可能发生 CIN,hs-CRP 的水平可作为辅助 CIN 诊断的指标。
出处 《广州医药》 2015年第5期61-63,共3页 Guangzhou Medical Journal
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