摘要
背景:研究发现,髋关节骨性关节炎患者全髋关节置换后下腰痛的症状得到一定缓解,提示下肢力线的改变对于腰痛症状具有明显的影响。目的:就髋-腰综合征的病理基础与生物力学机制进行综述并予以分析。方法:计算机检索1976年1月至2015年3月Pub Med数据库、中国期刊全文数据库的相关文章,英文检索词"low back pain,hip-spine syndrome,hip osteoarthritis,total hip replacement,biomechanics,balance parameters";中文检索词"下腰痛,髋-腰综合征,髋骨关节炎,髋关节置换,生物力学,平衡参数"。排除重复性研究及部分相关性较低的基础类文章。结果与结论:共计检索出145篇中英文文献,最终选择62篇文献进行综述。在病理生理中,肿瘤坏死因子α、白细胞介素1β和基质金属蛋白酶等对髋-腰综合征的发生发展起着十分重要的作用。而生物力学中,脊柱-骨盆-下肢平衡代偿过程成为髋-腰综合征的主要力学机制,其平衡参数可为髋-腰综合征的诊断,治疗及术后评估提供依据。
BACKGROUND： Low back pain in patients with hip osteoarthritis can be relieved to some extent after total hip arthroplasty, indicating the changes in limb line of force have obvious effects on low back pain. OBJECTIVE： To review and analysis the pathological base and biomechanics mechanism of hip-spine syndrome. METHODS： We retrieved PubMed database and China National Knowledge Infrastructure for related articles published from January 1976 to March 2015. The key words were ＂low back pain, hip-spine syndrome, hip osteoarthritis, total hip replacement, biomechanics, balance parameters＂ in English and Chinese, respectively. Repeated studies and unrelated articles were excluded. RESULTS AND CONCLUSION： A total of 145 articles were retrieved, and finally 62 articles were enrolled in result analysis. In the pathophysiology, tumor necrosis factor-α, interleukin-1β and matrix metalloproteinases play a significant role in the occurrence and development of hip-spine syndrome. As for the biological biomechanics, the spine-pelvic-lower limb balance compensatory process can be the main mechanical mechanism of hip-spine syndrome, and the balance parameters can provide a basis for the diagnosis, treatment and postoperative evaluation of hip-spine syndrome.
出处
《中国组织工程研究》
CAS
北大核心
2015年第33期5371-5377,共7页
Chinese Journal of Tissue Engineering Research
基金
江西省自然科学基金资助项目(20132BAB205067)~~
