期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

甲状腺癌移植瘤裸鼠模型研究进展 被引量：1

Progress in research on human thyroid cancer xenograft nude models
原文传递
导出
摘要 甲状腺癌是最常见的内分泌恶性肿瘤.甲状腺癌移植瘤裸鼠模型的建立对甲状腺癌的研究具有重要的价值,然而不同小鼠模型具有各自相应的特点和局限,需要根据实验的需要选择合适的小鼠模型.笔者将从常见的甲状腺癌移植瘤裸鼠模型研究进展方面进行相关综述. Thyroid cancer is the most common malignant endocrine tumor.The xenograft nude mice model of thyroid cancer have played an important role in studying thyroid cancer.Different mouse model has distinctive characters and limitations,so it is important to choose a suitable mice model due to the experiment purpose.In this paper,the authors will address the research progress of human thyroid cancer xenograft nude models.
作者 殷德涛 雷梦园
机构地区 郑州大学第一附属医院甲状腺外科、河南省高等学校临床医学重点学科开放实验室
出处 《国际外科学杂志》 2015年第8期551-554,共4页 International Journal of Surgery
基金 国家自然科学基金（No.81372863） 郑州市科技领军人才项目（No.131PLJRC676）
关键词 甲状腺肿瘤 移植瘤 小鼠 模型动物 Thyroid neoplasms Xenograft Mice Models,animal
分类号 R736.1 [医药卫生—肿瘤]
  • 相关文献

参考文献21

  • 1Yin D, Wu W, Li M, et al. DKK3 is a potential tumor suppressor gene in papillary thyroid carcinoma [ J]. Endocr-Relat cancer, 2013, 20(4) : 507-514.
  • 2Garcia M, Velez R, Romagosa C, et al. Cyclooxygenase-2 inhibi- tor suppresses tumour progression of prostate cancer bone metastases in nude mice[J]. BJUInt, 2014, ll3(5BSI): E164-E177.
  • 3殷德涛,雷梦园.甲状腺癌靶向研究的热点与展望[J].中国普通外科杂志,2015,24(5):623-626. 被引量：9
  • 4Yin G, Tang D, Dai J, et al. Combination efficacy of astragalus membranaceus and curcuma wenyujin at different stages of tumor progression in an imageable orthotopic nude mouse model of meta- static human ovarian cancer expressing red fluorescent protein [ J ]. Anticancer Res, 2015, 35(6): 3193-3207.
  • 5许建辉,殷德涛.CCDC与恶性肿瘤的研究进展[J].国际外科学杂志,2014,41(9):635-638. 被引量：12
  • 6Qiu w, Su GH. Challenges and advances in mouse modeling for human pancreatic tumorigenesis and metastasis[ J]. Cancer Metas- tasis Rev, 2013, 32(1-2SI) : 83-107.
  • 7Chang J, Yeh KY, Shen YC, et al. Production of multiple cyto-kines and induction of cachexia in athymic nude mice by a new ana- plastic thyroid carcinoma cell Iine [ J]. J Endocrinol, 2003, 179 (3) : 387-394.
  • 8Kim S, Park YW, Schiff BA, et al. An orthotopie model of ana- plastic thyroid eareinoma in athymie nude mice [ J 1. Clin Cancer Res, 2005, 11(5) : 1713-1721.
  • 9Bauer AJ, Patel A, Terrell R, et al. Systemic administration of vascular endothelial growth faetor monoelonal antibody reduces the growth of papillary thyroid eareinmna in a nude mouse model [J]. Ann Clin Lab Sei, 2003, 33(2) : 192-199.
  • 10Ahn S, Henderson Y, Kang Y, et al. An orthotopie model of pa- pillary thyroid carcinoma in athymic nude mice[J]. Arch Otolaryn- gol Head Neck Surg, 2008, 134(2) : 190-197.

二级参考文献48

  • 1Burkhard P,Stetefeld J,Strelkov SV.Coiled coils:a highly versatile protein folding motif[J].Trends Cell Biol,2001,11(2):82-88.
  • 2Murphy GA,Spedale EJ,Powell ST,et al.The Sir4 C-terminal coiled coil is required for telomeric and mating type silencing in Saccharomyces cerevisiae[J].J Mol Biol,2003,334(4):769-780.
  • 3Maeyama Y,Otsu M,Kubo S,et al.Intracellular estrogen receptor-binding fragment-associated antigen 9 exerts in vivo tumor-promoting effects via its coiled-coil region[J].Int J Oncol,2011,39(1):41-49.
  • 4Kobayashi S,Fukuhara A,Taguchi T,et al.Identification of a new secretory factor,CCDC3/Favine,in adipocytes and endothelial cells[J].Biochem Biophys Res Commun,2010,392(1):29-35.
  • 5Huang J,Zhang L,Liu W,et al.CCDC134 interacts with hADA2a and functions as a regulator of hADA2a in acetyltransferase activity,DNA damage-induced apoptosis and cell cycle arrest[J].Histochem Cell Biol,2012,138(1):41-55.
  • 6Huang J,Shi T,Ma T,et al.CCDC134,a novel secretory protein,inhibits activation of ERK and JNK,but not p38 MAPK[J].Cell Mol Life Sci,2008,65(2):338-349.
  • 7Zhong J,Zhao M,Luo Q,et al.CCDC134 is down-regulated in gastric cancer and its silencing promotes cell migration and invasion of GES-1 and AGS cells via the MAPK pathway[J].Mol Cell Biochem,2013,372(1/2):1-8.
  • 8Park SJ,Jang HR,Kim M,et al.Epigenetic alteration of CCDC67 and its tumor suppressor function in gastric cancer[J].Carcinogenesis,2012,33(8):1494-1501.
  • 9Najafov A,Alessi DR.Uncoupling the Warburg effect from cancer[J].Proc NatlAcadSciUSA,2010,107(45):19135-19136.
  • 10Tsolakis AV,Grimelius L,Islam MS.Expression of the coiled coil domain containing protein 116 in the pancreatic islets and endocrine pancreatic tumors[J].Islets,2012,4(5):349-353.

共引文献19

同被引文献3

引证文献1

二级引证文献1

国际外科学杂志
2015年 第8期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部