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青年男性雄激素性秃发与动脉粥样硬化危险因素的相关性研究 被引量:2

Correlative Analysis between Androgenetic Alopecia and Atherosclerosis in Young Men
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摘要 目的分析雄激素性秃发与动脉粥样硬化危险因素之间的相关性,探索雄激素性秃发成为动脉粥样硬化的早期预警信号的可能性。方法采用病例对照研究方法,比较62例雄激素性秃发患者与60例无秃发的健康体检者体重指数(BMI)、血压(BP)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、载脂蛋白A1(ApoA1)、载脂蛋白B(ApoB)、脂蛋白a(Lp(a))、载脂蛋白E(ApoE)、空腹血糖(FPG)、超敏C反应蛋白(hs-CRP)等动脉粥样硬化危险因素,分析两组反应血管弹性的超声前臂反应性充血试验(FMD)、脉搏波传导速度(BaPWV)、大动脉顺应性/小动脉顺应性(C1/C2)等动脉粥样硬化早期诊断指标。结果雄激素性秃发患者BMI、BP、TC、LDL-C、TC/HDL-C、LDL-C/HDL-C、ApoB、ApoB/ApoA1及BaPWV较无秃发的健康体检者均明显增高,而FMD明显降低。结论青年男性雄激素性秃发与动脉粥样硬化之间存在一定的相关性,雄激素性秃发可能是动脉粥样硬化血管疾病早期预警信号之一。 Objective To analyze the correlation between androgenetic alopecia and atherosclerosis . Methods Blood pressure (BP), body mass index (BMI), total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol ( LDL-C) , high-density lipoprotein cholesterol ( HDL-C) , TC/HDL-C, LDL-C/HDL-C, apolipoprotein A1 (ApoA1), apolipoprotein B (ApoB), ApoB/ApoA1, fasting plasma glucose ( FPG) , high-sensitivity C-reactive protein ( hs-CRP) and other clinical indicators in 144 cases of young men (18-35 years) with androgenetic alopecia(case group) and 60 cases of non-bald physical examinees(control group) were detected.Flow-mediated dilatation (FMD), pulse wave velocity (BaPWV) and aorta compliance/arterial compliance ( C1/C2 ) were compared .The association between androgenetic alopecia and atherosclerosis was investigated by case-control study.Results Case group had higher BP, BMT, TC, LDL-C, TC/HDL-C, LDL-C/HDL-C, ApoB, ApoB/ApoA1, BaPWV and lower FMD than control group (P〈0.05).Conclusion There is a correlation between androgenetic alopecia and atherosclerosis in young men .
出处 《湖北科技学院学报(医学版)》 2014年第2期93-95,共3页 Journal of Hubei University of Science and Technology(Medical Sciences)
基金 广东省科技计划(2010 B 031600305)
关键词 青年男性 雄激素性秃发 动脉粥样硬化 Young men Androgenetic alopecia Atherosclerosis
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参考文献7

  • 1Norwood OT.Male pattern baldness:classification and incidence[J].South Med J,1975,68(11):1359.
  • 2Ludwig E.Classification of the types of androgenetic alopecia(common baldness)occurring in the female sex[J].Br J Dermatol,1977,97(3):247.
  • 3向红丁.全国糖尿病流行病学调查方案[J].中国糖尿病杂志,1993,1(1):58-61. 被引量:10
  • 4刘力生.2004年中国高血压防治指南(实用本)[J].中华心血管病杂志,2004,32(12):1060-1064. 被引量:2620
  • 5王婷琳,沈佚葳,周城,王晓燕,丁晓岚,田珊,刘盈,彭光辉,薛树旗,周俊娥,王仁利,孟雪梅,裴广德,白云花,刘青,李航,陈捷,蔡林,张建中.我国6省雄激素性秃发流行病学调查[J].临床皮肤科杂志,2010,39(12):743-746. 被引量:23
  • 6Matilainen VA,Ma kinen PK,Keina nen-Kiukaanniemi SM.Early onset of androgenetic alopecia associated with early severe coronary heart disease:a population-based,case-control study[J].J Cardiovasc Risk,2001,8(3):147.
  • 7Serge A,Philippe LT,Béatrice C,et al.Association of androgenetic alopecia and hypertension[J].Eur J Dermatol,2007,17(3):220.

二级参考文献16

  • 1Hamilton JB.Patterned loss of hair in man:types and incidence[J].Ann NY Acad Sci,1951,53:708-728.
  • 2Ludwig E.Classification of the types of androgenetic alopecia (common baldness) occurring in the female sex[J].Br J Dermatol,1977,97(3):247-254.
  • 3Birch MP,Messenger JF,Messenger AG.Hair density,hair diameter and the prevalence of female pattern hair loss[J].Br J Dermatol,2001,144(2):297-304.
  • 4Norwood OT.Incidence of female androgenetic alopocia (female pattern alopecia)[J].Dermatol Surg,2001,27(1):53-54.
  • 5Rhodes T,Girman CJ,Savin RC,et al.Prevalence of male pattern hair loss in 18-49 year old men[J].Dermatol Surg,1998,24(12):1330-1332.
  • 6Severi G,Sinclair R,Hopper JL,et al.Androgenetie alopeciain men aged 40-69 years:prevalence and risk factors[J].Br J Dermatol,2003,149(6):1207-1213.
  • 7DeMuro-Mercon C,Rhodes T,Girman CJ,et al.Mah-pattern hair loss in Norwegian men:a community-based study[J].Dermatology,2000,200(3):219-222.
  • 8Desmond CC,Gan DC,Sinclair RD.Prevalence of male and female pattern hair loss in Maryborough[J].J Investig Dermatol Symp Proc,2005,10(3):184-189.
  • 9Khumalo NP,Jessop S,Gumedze F,et al.Hairdressing and the prevalence of scalp disease in African adults[J].Br J Dermatol,2007,157(5):981-988.
  • 10Paik JH,Yoon JB,Sim WY,et al.The prevalence and types of androgenetic alopecia in Korean men and women[J].Br J Dermatol,2001,145(1):95-99.

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