摘要
目的：对比右美托咪定和咪达唑仑用于患者清醒气管插管镇静的效果。方法本次研究对象取2014年3月～2015年3月期间来我院就诊的100例颌面部外伤骨折麻醉手术病例，根据随机数字表法将其均分为对照组与观察组各50例，对照组应用咪达唑仑，观察组应用右美托咪定静脉输注，对比两组呼吸指标、插管耐受情况以及血流动力学波动情况，并对研究结果相关数据作统计学处理。结果与对照组相比，观察组 MAP、PETCO2、HR 以及 SpO2各项指标更优，组间差异显著而具有统计学意义（P ＜0.05）；观察组插管耐受率更高，与对照组相比差异具有统计学意义（P ＜0.05）。结论在清醒气管插管镇静用药方案中，右美托咪定不会产生呼吸抑制，且患者用药后血流动力学无明显波动，效果更优于咪达唑仑，是较为理想的一种临床麻醉辅助用药。
Objective To compare the right beauty holds the mi and midazolam for patients with conscious endotracheal intubation calming effect. Methods The study object in March 2014 to March 2015 to our hospital during the period of 100 cases with fracture of maxillofacial trauma anesthesia surgery cases, according to random number table method to each 50 cases were divided into control group and observation group, control group using midazolam, observation group application right beautiful mi set by intravenous infusion, compared two groups of respiratory index, tolerance and intubation hemodynamic fluctuations, and the research results related data for statistical processing. Results Compared with control group, the observation group MAP, PErCO2, HR, SpO2 better indicators, significant difference between groups with statistical significance （P〈0.05）, Observation group intubation tolerance rate is higher, compared with the control group statistically significant difference （P〈0.05）. Conclusion In conscious endotracheal intubation calm regimen, the right beauty microphones set won＇t produce respiratory depression, and patients with hemodynamic no obvious fluctuation, the medicine effect is more better than that of midazolam, is a kind of ideal auxiliary medicine clinical anesthesia.
出处
《中国继续医学教育》
2015年第25期57-58,共2页
China Continuing Medical Education
关键词
气管插管
镇静药物
咪达唑仑
右美托咪定
血流动力学
呼吸抑制
The trachea intubation
Sedative drugs
Midazolam
Dexmedetomidine
Blood flow dynamics
Respiratory depression
