摘要
目的探讨罗哌卡因与布比卡因在剖宫产手术腰-硬联合麻醉中效果。方法分析2015年1-6月榆林市北方医院妇产科收治的孕产妇150例临床资料,依据麻醉药物不同进行分组,罗哌卡因组80例和布比卡因组70例。观察两组孕产妇给药前、给药后5 min、给药后10 min平均动脉压、心率、血氧饱和度的变化情况;观察两组孕产妇感觉阻滞起效时间、感觉最高阻滞平面、感觉阻滞最高平面时间、感觉阻滞持续时间、运动阻滞起效时间、运动最大阻滞时间、运动阻滞恢复时间、麻醉疗效评价情况、术后不良反应发生率情况。结果两组孕产妇给药前、给药后5 min、给药后10 min平均动脉压、血氧饱和度比较,差异无统计学意义（P〉0.05）。两组孕产妇给药前心率比较,差异无统计学意义（P〉0.05）,但是布比卡因组给药后5 min、给药后10 min心率均低于罗哌卡因组,布比卡因组孕产妇感觉阻滞起效时间、感觉最高阻滞平面、感觉阻滞最高平面时间、感觉阻滞持续时间、运动阻滞起效时间、运动最大阻滞时间均低于罗哌卡因组,布比卡因组孕产妇运动阻滞恢复时间高于布比卡因组,差异均有统计学意义（P〈0.05）。两组孕产妇麻醉疗效优良率差异无统计学意义（P〉0.05）。布比卡因组孕产妇术后不良反应发生率高于罗哌卡因组,差异有统计学意义（P〈0.05）。结论罗哌卡因与布比卡因用于剖宫产手术腰-硬联合麻醉效果无明显差异,但是罗哌卡因不良反应相对较少,值得临床推广应用。
Objective To explore the effect Ropivacaine and Bupivacaine in combined spinal-epidural anesthesia of cesarean section. Methods From January to June 2015, clinical data of 150 pregnant women in Department of Obstet- rics and Gynecology, the North Hospital of Yulin City were analyzed, and patients were divided into two groups by different narcotic drug, 80 cases of Ropivacaine group and 70 cases of Bupivacaine group. The MAP, HR, SPO2 of two groups before delivery and 5, 10 min after delivery were detected; the sensory blockade working time, feel highest block plane, sensory blockade the highest plane of time, duration of sensory blockade, motion block work time, the largest time of movement block, motion block recovery time, anesthesia efficacy evaluation, incidence of postoperative adverse reaction of two groups were detected. Results The MAP, SPO2 of two groups before delivery and 5, 10 min after delivery had no statistically significant differences （P 〉 0.05）. The HR of two groups cesarean delivery of maternal before delivery of difference had no statistically significant difference （P 〉 0.05）; but the HR of Bupivacaine group 5, 10 min after delivery was lower than that of the Ropivacaine group, the sensory blockade working time, feel highest block plane sensory blockade the highest plane of time, duration of sensory blockade, motion block work time, the largest time of movement block of Bupivacaine group were lower than those of the Ropivacaine group, the motion block recovery time of Bupivaeaine group were higher than those of the Ropivacaine group, the differences were statistically significant （P 〈 0.05）. The rate of good anesthetic effect showed no significant difference between two groups （P〉 0.05）. The incidenee of postoperative adverse reaction of Bupivaeaine group was higher than that of the Ropivacaine group, the difference was statistical significance （P 〈 0.05）. Conclusion There is no obvious difference in anesthetic effect between Ropivaeaine and Bupivacaine in combined spinal-epidural anesthesia of caesarean section by, but untoward effect of Ropivacaine is relatively few, it is worthy of clinical application.
出处
《中国医药导报》
CAS
2015年第28期63-66,共4页
China Medical Herald
关键词
罗哌卡因
布比卡因
剖宫产
腰-硬联合麻醉
Ropivacainei Bupivacaine
Caesarean section
Combined spinal-epidural anesthesia
