1International Agency for Research on Cancer. World Cancer Report 2008. Lyon, France: World Health Organization, 2008:374-378.
2Boland CR, Goel A. Microsatellite instability in colorectal cancer. Gastroenterology, 2010,138(6):2073-2087.
3Lynch HT, Lynch PM, Lanspa S J, et ai. Review of the Lynch syn- drome:history, molecular genetics, sereening,diferential diagnosis, and medicolegal ramifications. Clin Genet, 2009,76 (1):1-18.
4Dunlop MG, Farrington SM, Nicholl I, et al. Population carrier fre- quency of hMSH2 and hMLH1 mutations. Br J Cancer, 2000,83(12): 1643-1645.
5Wheeler JM, Bodmer WF, Mortensen NJ. DNA mismatch repair genes and colorectal cancer. Gut, 2000,47(1):148-153.
6lyer RR1, Pluciennik A, Burdett V, et al. DNA mismatch repair: functions and mechanisms.Chem Rev, 2006, 106(2):302-320.
7Chang EY, Dorsey PB, Frankhouse J, et al. Combination ofmi- crosatellite instability and lymphocytic infiltrate as a prognostic in- dicator in colon cancer. Arch Surg, 2009,144(6):511-515.
8Nagasaka T, Koi M, Kloor M, et al. Mutations in both KRAS and BRAF may contribute to the methylator phenotype in colon cancer. Gastroenterology, 2008,134(7): 1950-1960.
9Duval A, Hamelin R. Mutations at coding repeat sequences in mis- match repair-deficient human cancers: toward a new concept of tar- get genes for instability. Cancer Res, 2002,62(9):2447-2454.
10Olschwang S, Bonaiti C, Feingold J, et al. Identification and man- agement of syndrome(hereditary nonpolyposis colon cancer), hered- itary predisposition to colorectal and endometrial. Bull Cancer, 2004,91(4,):303-315.
2Rosenwald A,Wright G,Chan WC,et al.The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma[J].N Engl J Med,2002,346:1937.
3Popat S,Hubner R,Houlston RS.Systematic review of microsatellite instability and colorectal cancer prognosis[J].J Clin Oncol,2005,23:609.
4Parc Y,Gueroult S,Mourra N,et al.Prognostic significance of microsatellite instability determined by immunohistochemical staining of MSH2 and MLH1 in sporadic T3N0M0 colon cancer[J].Gut,2004,53:371.
5Samowitz WS,Curtin K,Ma KN,et al.Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level[J].Cancer Epidemiol Biomarkers Prev,2001,10:917.
6Gryfe R,Kim H,Hsieh ET,et al.Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer[J].N Engl J Med,2000,342:69.
7Emterling A,Wallin A,Arbman G,et al.Clinicopathological significance of microsatellite instability and mutated RIZ in colorectal cancer[J].Ann Oncol,2004,15:242.
8Ribic CM,Sargent DJ,Moore MJ,et al.Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer[J].N Engl J Med,2003,349:247.
9Peltomki P.Deficient DNA mismatch repair:a common etiologic factor for colon cancer[J].Hum Mol Genet,2001,10:735.
10Umar A,Boland CR,Terdiman JP,et al.Revised bethesda guidelines for hereditary nonpolyposis colorectal cancer(Lynch syndrome) and microsatellite instability[J].J Natl Cancer Inst,2004,96(4):261.