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杯状细胞在肠道疾病发病中作用的研究进展 被引量:24

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摘要 肠道杯状细胞作为肠道上皮细胞中的分泌型细胞,其分泌的黏蛋白(MUC)、肠三叶因子(ITF)和抵抗素样分子β(RELMβ)等成分构成肠道表面覆盖的一层保护性黏液屏障,是肠道固有免疫第一防线的重要组成部分。以杯状细胞为基础的黏蛋白对维持肠道黏膜的完整和稳定具有重要作用,并参与感染、坏死性肠炎、炎症性肠病等多种肠道疾病的发生发展。该文就杯状细胞在肠道疾病发病中作用的研究进展作一综述。
出处 《国际消化病杂志》 CAS 2015年第4期244-246,269,共4页 International Journal of Digestive Diseases
基金 国家自然科学基金资助项目(81070283 81300272) 高等学校博士学科点专项科研基金(20121202110018) 天津市应用基础与前沿技术研究计划(13JCQNJC10600)
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