摘要
目的:分析并探讨前列腺穿刺活检中血清高敏C反应蛋白(hs-CRP)测定的临床意义。方法:选取2012年2月至2015年2月期间在我院接受前列腺穿刺活检患者275例。病理诊断为良性前列腺增生(BPH)患者178例,病理诊断为PCa患者97例。检测患者hs-CRP含量及其他各项指标含量。结果:BPH患者hs-CRP为(1.24±0.37)mg/L,PCa患者hs-CRP为(3.21±0.89)mg/L。PCa患者hs-CRP明显高于BPH患者。经统计学检验,差异具有统计学意义(P<0.05)。hs-CRP升高(大于3mg/L)患者93例,其中PCa52例,穿刺阳性率为55.91%。hs-CRP正常(小于等于3mg/L)患者182例,其中PCa45例,穿刺阳性率为24.73%。hs-CRP升高穿刺阳性率明显升高。经统计学检验,差异具有统计学意义(P<0.05)。年龄、t PSA、TPV和hs-CRP是影响前列腺穿刺阳性率的独立因素(P<0.05)。结论:血清高敏C反应蛋白是影响前列腺穿刺阳性率的独立因素,当血清高敏C反应蛋白升高时,穿刺阳性率明显升高,对于疾病诊断具有提示作用。
Objectives：To analyze and discuss the clinical significance of prostate biopsy in patients with serum high -sensitivity C -reactive protein measurement.Methods：275 patients received prostate biopsy in our hospital from February 201 2 to February 201 5 were selected.There were 1 78 cases of benign prostatic hyperplasia （BPH）and 97 cases of PCa.Hs -CRP and other indexes content were measured.Results：Hs -CRP of BPH pa-tients and PCa patients was （1 .24 ±0.37）mg /L and （3.21 ±0.89）mg/L respectively,with statistically sig-nificant difference （P 〈0.05）.There were 93 cases with increasing hs -CRP （greater than 3mg /L）,of which there were 52 cases of PCa and the positive biopsy rate was 55.91 %.There were 1 82 cases with normal hs -CRP （less than or equal 3mg /L）,of which there were 45 cases of PCa and the positive biopsy rate was 24.73%.The positive rate of increasing hs -CRP group was significantly higher,with statistically significant difference （P 〈0.05）.Independent factors affecting prostate biopsy positive rate were age,tPSA,TPV and hs -CRP （P 〈0.05）. Conclusion：The serum high -sensitivity C -reactive protein is an independent factor affecting the positive rate of prostate biopsy.As serum high -sensitivity C -reactive protein increases,the positive rate is significantly higher, which can be used as prompted action.
出处
《中国性科学》
2015年第8期8-10,共3页
Chinese Journal of Human Sexuality
基金
国家自然科学基金面上项目(81172434)
关键词
前列腺增生
前列腺肿瘤
血清高敏
C
反应蛋白
穿刺活检
Benign homeostatic hyperglycemia
Prostate cancer
Serum high -sensitivity C -reac-tive protein
Biopsy
