摘要
目的:观察不同疾病患者行眼底荧光血管造影(flourescence fundus angiography,FFA)的方法和对不良反应的防范。方法:患者签署知情同意书后,双眼散瞳,所有病例常规行双眼裂隙灯和直接、间接眼底镜检查,拍摄双眼的彩色眼底照片,静脉注射1%荧光素钠注射液5 m L,观察15 min,无任何不良反应后快速静脉推注10%荧光素钠注射液4.5 m L,采用Topcon TRC-50EX眼底照相系统进行检查。结果:2 841例患者均顺利完成造影,其中糖尿病性视网膜病变1 031例、高血压性眼底改变530例、视网膜静脉阻塞382例、黄斑病变162例、眼外伤113例、中心性浆液性和渗出性脉络膜视网膜病89例、变性近视眼底改变72例、原发性视网膜色素变性68例、黄斑裂孔61例、黄斑视网膜前膜58例、血管炎55例、视网膜血管炎51例、视乳头缺血性视乳头病变38例、视网膜动脉阻塞37例、Stargardt病18例、旁中心凹视网膜毛细血管扩张症13例、其他眼病63例;23例患者转上级医院进行进一步确诊;发生不良反应132例(4.6%),未发生严重不良反应事件。结论:在眼底荧光血管造影检查中,临床医生要做好各项应急预防措施,根据患者的病情种类、有无合并症等制定规范的个体化拍摄计划,提高操作和诊断水平以及对不良反应的观察和处理能力,获得理想的眼底荧光血管造影图像,为眼底病的诊断、治疗提供可靠的依据。
Objective： To investigate the methods of fundus fluorescein angiography（ FFA） performed in patients with different diseases and the prevention of adverse reaction. Methods： Each participant signed written informed consent. After going through mydriasis,all patients were examined by slit lamp examination and indirect or direct fundus ophthalmoscope. Meanwhile,colourful eye fundus images were taken. All patients were injected sodium fluorescein（ 1 %） 5 m L,and observed 15 minutes,after which sodium fluorescein（ 10 %） 4. 5 m L was injected rapidly if without any adverse reaction. And then they were examined by fundus camera system（ Topcon TRC- 50E）. Results： 2 841 cases had successfully finished examination. There were 1 031 patients with diabetic retinopathy,530 patients with hypertension retinopathy,382 patients with retinal vein occlusion,162 patients with maculopathy,113 patients with ocular trauma,89 patients with central serous and exudative chorioretinopathy,72 patients with fundus change of degenerative myopia,68 patients with primary retinitis pigmentosa,61 patients with macular hole,58 patients with macular epiretinal membranes,55 patients with vasculitis,51 patients with retinal vasculitis,38 patients with ischemic lesions of optic nerve head,37 patients with retinal artery occlusion,18 patients with Stargardt disease,13 patients with retinal telangiectasis,and 63 patients with other diseases. 23 patients transfered to upper- grade hospital for further diagnosis. The adverse reaction appeared in 132 cases with no severe adverse effect during the period. Conclusion： During fundus fluorescein angiography,each item of preventive measures of emergency need to be well- prepared for clinical doctors,and normative shooting plan tailored for individuals was established according to the types of patients＇ diseases,and the occurrence of severe complications or not. Therefore,diagnostic and operation level and the ability to treat the adverse reaction will be enhanced,so as to provide the reliable guidance for acquiring the ideal image of FFA and for diagnosing and treating fundus diseases.
出处
《包头医学院学报》
CAS
2015年第9期24-25,共2页
Journal of Baotou Medical College
关键词
眼底
荧光造影
基层医院
不良反应
Fundu
Fluorescein angiography
Primary
Adverse reaction
