摘要
目的 总结胸腺肽配合化疗治疗 2 5例恶性淋巴瘤的疗效及对免疫细胞活性的影响。方法 分别测定治疗组、对照组和治疗前后T淋巴细胞亚群的变化并分析临床疗效。结果 完全缓解 1 0例 ,部分缓解 1 5例 ,有效率 1 0 0 % ,治疗前后测定CD+ 3 ,CD+ 4,CD+ 4/CD+ 8比值、NK细胞活性均明显高于治疗前 (P <0 .0 5 )。结论 胸腺肽可提高恶性淋巴瘤化疗患者的免疫功能 ,肿瘤缓解率高 。
Objective We observed peripheral blood T cell and NK cell activity before and after chemotherapy plus thymopeptides in lymphoma patients and clinical effects. Methods To divide into three groups: before and after chemotherapy plus thypopeptide groups and benign diseases group (control). Results Before treatment, the immune indeses of lymphoma were lower than those of control. After treatment, the immunocyte CD + 3, CD + 4, CD + 4/CD + 8, NK activity were significatly greater than before treatment, clinical symptoms had improved. Conclusion The thymopeptides can increase the immunity function of lymphoma under chemotherapy and improve the patients clinical symptoms.
出处
《临床军医杂志》
CAS
2002年第4期15-16,共2页
Clinical Journal of Medical Officers
