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经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折的临床效果

Clinical outcomes of percutaneous kyphoplasty for osteoporotic vertebral fractures
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摘要 目的评估经皮椎体后凸成形术对骨质疏松椎体压缩骨折的临床疗效。方法将50例骨质疏松椎体压缩骨折患者随机分为试验组与对照组,试验组患者采取经皮椎体后凸成形术治疗,对照组患者采取常规经皮椎体成形术治疗,比较两组患者视觉模拟评分(VAS)、Oswestry评分以及4项影像学指标(后凸角以及伤椎前缘、中线、后缘高度)变化。结果两组患者术后VAS评分均显著下降(P<0.05),但试验组下降幅度更大(P<0.05);两组患者术后Oswestry评分均显著下降(P<0.05),但试验组下降幅度较对照组更大(P<0.05);试验组患者后凸角以及伤椎前缘、中线、后缘高度术后均显著改善(P<0.05),而对照组手术前后差异无统计学意义(P>0.05)。结论采用经皮椎体后凸成形术治疗骨质疏松椎体压缩骨折疗效优于经皮椎体成形术,但经皮椎体后凸成形术治疗成本高于经皮椎体成形术。今后应根据患者实际情况选择术式。 Objective To evaluate the clinical efficacies of percutaneous kyphoplasty (PKP) in treatment of osteoporotic vertebral fractures. Methods Fifty patients with osteoporotic vertebral fractures were randomly allocated to observational group and control group. The observational group received PKP treatment, and the controls were given conventional percutaneous vertebroplasty (PVP). Then the two groups were compared concerning the changes of Visual Analogue Score(VAS), Oswestry Disability Index and imaging findings(includ-ing changes at the posterior angular kyphosis, injured vertebral body, middle and posterior height). Results Both VAS scores and Oswestry scores were significantly lower in the two groups after treatment, yet the chang-es were more notable in observational group, with particular improvement on the posterior angular kyphosis, injured vertebral body, middle and posterior height(P〈0.05). The control group remained no significant change compared to pre-treatment(P〉0.05). Conclusion PKP has better curative effect, yet higher medical cost than PVP, for which the surgical option should rely on the patient’s condition.
机构地区 沈阳军区总医院
出处 《热带病与寄生虫学》 2015年第3期172-174,共3页 Journal of Tropical Diseases and Parasitology
关键词 经皮椎体后凸成形术 经皮椎体成形术 骨质疏松症 椎体压缩性骨折 临床疗效 Percutaneous kyphoplasty Percutaneous vertebroplasty Osteoporosis Vertebral com-pression fracture Clinical efficacy
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